MS4A3 and TMEM218

Data Source:
BioGRID (two hybrid)

		MS4A3	TMEM218
Description		membrane spanning 4-domains A3	transmembrane protein 218
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm	Cilium Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Neutrophil Degranulation Regulation Of Cell Cycle
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)	Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)
Interacting Genes		38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1	72 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR
Entrez ID		932	219854
HPRD ID		09403	19054
Ensembl ID		ENSG00000149516	ENSG00000150433
Uniprot IDs		Q96HJ5	A2RU14
PDB IDs
Enriched GO Terms of Interacting Partners?
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