MS4A3 and ATP6V0B

Data Source:
BioGRID (two hybrid)

		MS4A3	ATP6V0B
Description		membrane spanning 4-domains A3	ATPase H+ transporting V0 subunit b
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm	Vacuolar Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	Protein Binding	Transporter Activity Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Neutrophil Degranulation Regulation Of Cell Cycle	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		Neutrophil degranulation	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1	28 interacting genes: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG
Entrez ID		932	533
HPRD ID		09403	04759
Ensembl ID		ENSG00000149516	ENSG00000117410
Uniprot IDs		Q96HJ5	E9PNL3 Q99437
PDB IDs
Enriched GO Terms of Interacting Partners?
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