MS4A3 and CDKN3

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		MS4A3	CDKN3
Description		membrane spanning 4-domains A3	cyclin dependent kinase inhibitor 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Neutrophil Degranulation Regulation Of Cell Cycle	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Peptidyl-tyrosine Dephosphorylation
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)	Dental caries ( 23259602) Endometrial cancer (Non-endometrioid histology) ( 30093612) High myopia ( 31816047) Metabolite levels ( 23823483) Metabolite levels (X-11787) ( 23934736) Monobrow thickness ( 26926045) Myopia ( 27182965) Refractive error ( 32231278) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
Interacting Genes		38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1	9 interacting genes: CDC25A CDK1 CDK2 CDK3 CEBPA MS4A3 NCOA3 PPP1R12A ROCK2
Entrez ID		932	1033
HPRD ID		09403	00450
Ensembl ID		ENSG00000149516	ENSG00000100526
Uniprot IDs		Q96HJ5	G3V2J7 Q16667
PDB IDs			1FPZ 1FQ1
Enriched GO Terms of Interacting Partners?
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