CHMP4C and STAMBP

Data Source:
BioGRID (pull down)

		CHMP4C	STAMBP
Description		charged multivesicular body protein 4C	STAM binding protein
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GO Annotations	Cellular Component	ESCRT III Complex Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Flemming Body	Nucleus Nucleoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome
	Molecular Function	Protein Binding Protein Homodimerization Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Protein Domain Specific Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Isopeptidase Activity
	Biological Process	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Regulation Of Viral Process Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell	Mitotic Cytokinesis Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Ras Protein Signal Transduction Protein K63-linked Deubiquitination
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Metalloprotease DUBs
Drugs
Diseases
GWAS		Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)	Anti-saccade response ( 29064472) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944)
Interacting Genes		10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	45 interacting genes: ALAS1 AMN APOBEC3A BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 NLRP3 NLRP7 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28
Entrez ID		92421	10617
HPRD ID		18135	05877
Ensembl ID		ENSG00000164695	ENSG00000124356
Uniprot IDs		Q96CF2	A0A140VK54 O95630
PDB IDs		3C3R 5MK3 5V3R 5WA1	2XZE 3RZU 3RZV 5IXF
Enriched GO Terms of Interacting Partners?
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