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PNMA1 and USP2
Data Source:
BioGRID
(two hybrid)
PNMA1
USP2
Description
PNMA family member 1
ubiquitin specific peptidase 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Nucleoplasm
Cytoplasm
Centrosome
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cyclin Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Apoptotic Process
Negative Regulation Of Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Muscle Organ Development
Protein Deubiquitination
Protein Phosphopantetheinylation
Circadian Regulation Of Gene Expression
Entrainment Of Circadian Clock By Photoperiod
Locomotor Rhythm
Positive Regulation Of Mitotic Cell Cycle
Circadian Behavior
Protein Stabilization
Pathways
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Ub-specific processing proteases
Regulation of TP53 Degradation
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Serum uric acid levels (
30993211
)
Urate levels (
31985003
31578528
23263486
)
Interacting Genes
167 interacting genes:
ABHD17A
AGTR1
ANKRD36BP1
APTX
ARHGEF6
ARID5A
ASMTL
ATP5PO
ATP6V1G1
ATXN7
BEX2
BYSL
C1orf109
C21orf58
C8orf33
CARHSP1
CBX8
CCDC146
CCDC187
CCDC198
CCDC33
CCNG1
CCP110
CDK18
CFAP53
CHIC2
CHMP2B
CNNM3
COX5B
CTNNA3
DAXX
DCTN4
EAF2
EHHADH
ENKD1
FAM107A
FAM110A
FAM161A
FAM161B
FBF1
FBXL18
FEM1C
FMNL2
FOXD4L1
FOXD4L3
GADD45GIP1
GATA1
GEM
GPANK1
GPR25
GRAP2
GTPBP10
HAPLN2
HCK
HDAC4
HGS
HNRNPLL
HOXB9
IGFN1
INO80B
IVD
KANSL1
KAT2B
LAGE3
LENG1
LIN37
LMO3
LNX1
LSM2
MAB21L2
MACIR
MARK4
MCM7
MED8
METTL17
MRPL10
MRPL11
MRPL23
MSI1
MYO15B
MYOZ1
NIF3L1
NPBWR2
NSMF
NTAQ1
NUDT16L1
PARD3
PARD6B
PCGF6
PER1
PIN1
PIN4
PKN1
PKN3
PNMA5
PNMA6A
POLDIP3
POLL
POLM
PRKAB2
PRKCG
PRKCI
PRPF18
PRPF31
PSMA1
RAD51D
RAPGEF3
RBM41
RPP25
RPP25L
RSPH9
RSRC2
RTP5
RUSC1
SCAND1
SCNM1
SDCBP
SEMA4C
SH2D4A
SHC3
SHISA3
SLC25A48
SLIRP
SMIM3
SNRPB
SNRPB2
SPATC1L
SPG7
SSX2IP
STAMBPL1
SUV39H2
TASOR2
TCEA2
TCEANC
TCL1B
TEAD4
TMSB4X
TNNI1
TNNT1
TRIM42
TRIM73
TRPV6
TSHZ2
TSPYL4
TTC23
TTC9C
TXNDC9
UBQLN1
UBQLN4
URB1-AS1
USP2
VAV2
VBP1
VPS9D1
WDR25
WT1-AS
ZC2HC1C
ZCCHC12
ZFYVE26
ZG16B
ZNF148
ZNF35
ZNF410
ZNF438
ZNF564
ZNF581
ZNF688
163 interacting genes:
ABI2
ACTN1
ACTN2
ACTN3
APP
ASPG
ATN1
AURKA
BAP1
BCAR1
BCL2L2-PABPN1
BEGAIN
BEND5
BHLHB9
BICD2
BIRC7
BRCA1
CADPS
CALCOCO2
CARD9
CBLC
CCDC136
CCDC57
CCDC85B
CCDC88B
CCND1
CEP63
CEP70
CRACR2A
CRACR2B
CRY1
CTNNB1
DDI1
DEPDC5
DISC1
DTX3
DUSP21
DYDC1
EFHC2
EIF4ENIF1
ENPP1
ERBB2
EXOC5
EXOSC8
GEMIN4
GOLGA2
GOLGA6A
GOLGA6L9
GRB7
GRIPAP1
H2AC20
HOMER3
HOOK1
HOOK2
IHO1
IKBKG
IKZF3
IL1RL2
INTS11
JAKMIP1
JRK
KAZN
KIFC3
KRT15
KRT27
KRT31
KRT33B
KRT34
KRT35
KRT40
LHX3
LHX4
LMNA
LMNB2
LNX2
LONRF1
LRSAM1
LZTS2
MALT1
MAP3K2
MDM2
MID2
MNAT1
MORN5
MRPL28
MTUS2
MYC
NAB2
NDEL1
NEFL
NFKB2
NOTCH1
OIP5
OPTN
ORC3
ORC5
PALB2
PCGF6
PCNA
PEX5
PIBF1
PICK1
PIK3R3
PLA2G2A
PLEKHG4
PNMA1
POU2AF1
PRDM14
PRR5L
RABEP1
RAD18
RBCK1
RFX6
RNF125
RNF126
RNF144B
RNF166
RUNDC3A
S100A10
SH2B2
SNCA
SORBS3
SPAG8
SPDYE4
STAT5B
TAX1BP1
TEKT4
TFIP11
TGFBR1
TLE5
TNFAIP2
TRAF1
TRAF2
TRAF6
TRAIP
TRIM21
TRIM23
TRIM27
TRIM34
TRIM35
TRIM39
TRIM46
TRIM5
TRIM50
TRIM54
TRIM63
TRIM74
TRIM8
TRIM9
TRIP6
UBE2S
UBOX5
USHBP1
USP15
USP21
USP54
VCAM1
VPS28
VPS52
ZAP70
ZBED1
ZIM2
ZRANB1
Entrez ID
9240
9099
HPRD ID
04926
05287
Ensembl ID
ENSG00000176903
ENSG00000036672
Uniprot IDs
Q8ND90
O75604
PDB IDs
2HD5
2IBI
3NHE
3V6C
3V6E
5XU8
5XVE
6DGF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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