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PNMA1 and IVD
Data Source:
BioGRID
(two hybrid)
PNMA1
IVD
Description
PNMA family member 1
isovaleryl-CoA dehydrogenase
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Mitochondrial Matrix
Mitochondrial Membrane
Molecular Function
Protein Binding
Butyryl-CoA Dehydrogenase Activity
Protein Binding
Isovaleryl-CoA Dehydrogenase Activity
Identical Protein Binding
Flavin Adenine Dinucleotide Binding
Biological Process
Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Apoptotic Process
Leucine Catabolic Process
Branched-chain Amino Acid Catabolic Process
Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase
Pathways
Branched-chain amino acid catabolism
Drugs
Flavin adenine dinucleotide
Coenzyme A persulfide
Diseases
Isovaleric acidemia (IVA)
GWAS
Blood metabolite levels (
24816252
)
Blood metabolite ratios (
24816252
)
Cognitive ability (
29186694
)
Cognitive ability (MTAG) (
29186694
)
FEV1 (
30804560
)
Idiopathic pulmonary fibrosis (
31710517
)
Intelligence (MTAG) (
29326435
)
Lung function (FVC) (
30804560
)
Malaria (
31844061
)
Metabolic traits (
21886157
)
Interacting Genes
167 interacting genes:
ABHD17A
AGTR1
ANKRD36BP1
APTX
ARHGEF6
ARID5A
ASMTL
ATP5PO
ATP6V1G1
ATXN7
BEX2
BYSL
C1orf109
C21orf58
C8orf33
CARHSP1
CBX8
CCDC146
CCDC187
CCDC198
CCDC33
CCNG1
CCP110
CDK18
CFAP53
CHIC2
CHMP2B
CNNM3
COX5B
CTNNA3
DAXX
DCTN4
EAF2
EHHADH
ENKD1
FAM107A
FAM110A
FAM161A
FAM161B
FBF1
FBXL18
FEM1C
FMNL2
FOXD4L1
FOXD4L3
GADD45GIP1
GATA1
GEM
GPANK1
GPR25
GRAP2
GTPBP10
HAPLN2
HCK
HDAC4
HGS
HNRNPLL
HOXB9
IGFN1
INO80B
IVD
KANSL1
KAT2B
LAGE3
LENG1
LIN37
LMO3
LNX1
LSM2
MAB21L2
MACIR
MARK4
MCM7
MED8
METTL17
MRPL10
MRPL11
MRPL23
MSI1
MYO15B
MYOZ1
NIF3L1
NPBWR2
NSMF
NTAQ1
NUDT16L1
PARD3
PARD6B
PCGF6
PER1
PIN1
PIN4
PKN1
PKN3
PNMA5
PNMA6A
POLDIP3
POLL
POLM
PRKAB2
PRKCG
PRKCI
PRPF18
PRPF31
PSMA1
RAD51D
RAPGEF3
RBM41
RPP25
RPP25L
RSPH9
RSRC2
RTP5
RUSC1
SCAND1
SCNM1
SDCBP
SEMA4C
SH2D4A
SHC3
SHISA3
SLC25A48
SLIRP
SMIM3
SNRPB
SNRPB2
SPATC1L
SPG7
SSX2IP
STAMBPL1
SUV39H2
TASOR2
TCEA2
TCEANC
TCL1B
TEAD4
TMSB4X
TNNI1
TNNT1
TRIM42
TRIM73
TRPV6
TSHZ2
TSPYL4
TTC23
TTC9C
TXNDC9
UBQLN1
UBQLN4
URB1-AS1
USP2
VAV2
VBP1
VPS9D1
WDR25
WT1-AS
ZC2HC1C
ZCCHC12
ZFYVE26
ZG16B
ZNF148
ZNF35
ZNF410
ZNF438
ZNF564
ZNF581
ZNF688
4 interacting genes:
ACTN3
GPSM3
MGAT5B
PNMA1
Entrez ID
9240
3712
HPRD ID
04926
09516
Ensembl ID
ENSG00000176903
ENSG00000128928
Uniprot IDs
Q8ND90
A0A0A0MT83
A0A0S2Z4K7
P26440
PDB IDs
1IVH
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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