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USP2 and TFIP11
Data Source:
BioGRID
(two hybrid)
USP2
TFIP11
Description
ubiquitin specific peptidase 2
tuftelin interacting protein 11
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Membrane
Perinuclear Region Of Cytoplasm
Chromosome, Telomeric Region
Nucleoplasm
Spliceosomal Complex
Nucleolus
Cytoplasm
Nuclear Speck
Extracellular Matrix
U2-type Post-mRNA Release Spliceosomal Complex
Catalytic Step 2 Spliceosome
Molecular Function
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cyclin Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Metal Ion Binding
Nucleic Acid Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Muscle Organ Development
Protein Deubiquitination
Protein Phosphopantetheinylation
Circadian Regulation Of Gene Expression
Entrainment Of Circadian Clock By Photoperiod
Locomotor Rhythm
Positive Regulation Of Mitotic Cell Cycle
Circadian Behavior
Protein Stabilization
Spliceosomal Complex Disassembly
MRNA Splicing, Via Spliceosome
RNA Processing
Biomineral Tissue Development
Negative Regulation Of Protein-containing Complex Assembly
Protection From Non-homologous End Joining At Telomere
Negative Regulation Of Protein Binding
Negative Regulation Of DNA Ligase Activity
Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Ub-specific processing proteases
Regulation of TP53 Degradation
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Serum uric acid levels (
30993211
)
Urate levels (
31985003
31578528
23263486
)
Interacting Genes
163 interacting genes:
ABI2
ACTN1
ACTN2
ACTN3
APP
ASPG
ATN1
AURKA
BAP1
BCAR1
BCL2L2-PABPN1
BEGAIN
BEND5
BHLHB9
BICD2
BIRC7
BRCA1
CADPS
CALCOCO2
CARD9
CBLC
CCDC136
CCDC57
CCDC85B
CCDC88B
CCND1
CEP63
CEP70
CRACR2A
CRACR2B
CRY1
CTNNB1
DDI1
DEPDC5
DISC1
DTX3
DUSP21
DYDC1
EFHC2
EIF4ENIF1
ENPP1
ERBB2
EXOC5
EXOSC8
GEMIN4
GOLGA2
GOLGA6A
GOLGA6L9
GRB7
GRIPAP1
H2AC20
HOMER3
HOOK1
HOOK2
IHO1
IKBKG
IKZF3
IL1RL2
INTS11
JAKMIP1
JRK
KAZN
KIFC3
KRT15
KRT27
KRT31
KRT33B
KRT34
KRT35
KRT40
LHX3
LHX4
LMNA
LMNB2
LNX2
LONRF1
LRSAM1
LZTS2
MALT1
MAP3K2
MDM2
MID2
MNAT1
MORN5
MRPL28
MTUS2
MYC
NAB2
NDEL1
NEFL
NFKB2
NOTCH1
OIP5
OPTN
ORC3
ORC5
PALB2
PCGF6
PCNA
PEX5
PIBF1
PICK1
PIK3R3
PLA2G2A
PLEKHG4
PNMA1
POU2AF1
PRDM14
PRR5L
RABEP1
RAD18
RBCK1
RFX6
RNF125
RNF126
RNF144B
RNF166
RUNDC3A
S100A10
SH2B2
SNCA
SORBS3
SPAG8
SPDYE4
STAT5B
TAX1BP1
TEKT4
TFIP11
TGFBR1
TLE5
TNFAIP2
TRAF1
TRAF2
TRAF6
TRAIP
TRIM21
TRIM23
TRIM27
TRIM34
TRIM35
TRIM39
TRIM46
TRIM5
TRIM50
TRIM54
TRIM63
TRIM74
TRIM8
TRIM9
TRIP6
UBE2S
UBOX5
USHBP1
USP15
USP21
USP54
VCAM1
VPS28
VPS52
ZAP70
ZBED1
ZIM2
ZRANB1
232 interacting genes:
AARD
ABI2
ABLIM3
AIMP2
ANKRD11
AP1M1
ARHGEF9
ARMC7
ARMCX1
ARNT2
ATP5PO
ATPAF2
AXIN1
BAZ2B
BCL6
BHLHA9
BMF
BRD1
BYSL
C1orf109
C2CD6
CARD9
CAVIN3
CBX8
CCDC102B
CCDC116
CCDC120
CCDC121
CCDC13
CCDC146
CCDC187
CCDC196
CCDC42
CCDC57
CCDC6
CCDC68
CCDC96
CCHCR1
CCND3
CCNG1
CCNL1
CCP110
CDKN1A
CDR2L
CENPU
CEP57
CEP57L1
CEP95
CFAP206
COQ8A
COX5B
CT55
CWF19L2
DAXX
DDX25
DES
DGCR6
DISC1
DPPA3
DTNB
EAF2
EIF3A
EIF3D
ENOX2
EPM2AIP1
EXOC3L1
EXOC8
EXOSC5
FAM13C
FAM156A
FAM161A
FAM161B
FAM50B
FAM81A
FAM90A1
FANCG
FGA
GADD45GIP1
GAS2L2
GCC1
GCFC2
GEM
GFAP
GNG4
GOLGA1
GOLGA2
GPS2
GRAP2
GSE1
HAUS1
HDAC4
HIP1R
HMG20B
HOOK1
HSF2BP
IKBIP
IL16
IMP3
JRK
KANK2
KANSL1
KAT5
KDM1A
KIF3C
KIF9
KIFC3
KIZ
KRT1
KRT20
KRT6A
KRT6B
KRT6C
KRT8
LATS1
LCA5
LCA5L
LENG1
LIN37
LMNB2
LMO1
LMO2
LMO4
LSM3
LSP1P3
LYSMD1
MAB21L2
MCM7
MDM2
METTL17
MFAP1
MKRN3
MRPL11
MTFR2
MXD3
MYO15B
MYOM1
NDC80
NDE1
NDN
NEK6
NFKBID
NFU1
NSMF
NUP88
ODAD3
OIP5
PBX3
PBX4
PCM1
PDE4DIP
PHF1
PIBF1
PICK1
PKN3
PLK4
POLL
POLR1C
POM121
PPFIA3
PPP1R16A
PPP1R16B
PPP1R18
PRPF31
PSMA4
PSMC5
PSTPIP1
PTCD1
RCOR3
RHNO1
RIN1
RNF6
RRP7A
RUNX1T1
RXRB
S100P
SAP30BP
SCNM1
SFR1
SGF29
SH2D4A
SH3GLB1
SMARCB1
SMARCE1
SNAPIN
SNRPB
SNW1
SNX20
SNX32
SOGA1
SPG21
SSX2IP
STRA8
STRN
SYCE1
TBC1D30
TBRG4
TCAF1
TDP2
TFPT
THAP7
THAP8
TNNT1
TP53
TRAF3IP3
TRAPPC4
TRIM45
TRIML2
TSG101
TSGA10IP
TSHZ2
TSHZ3
TSPYL4
TUFT1
TXLNA
TXN2
UBTFL1
USP2
USP6
USP7
VPS37C
VPS39
WAC
WASHC3
ZC2HC1C
ZFYVE26
ZGPAT
ZMAT2
ZNF417
ZNF572
ZNF587
ZNF777
ZSCAN12
Entrez ID
9099
24144
HPRD ID
05287
11628
Ensembl ID
ENSG00000036672
ENSG00000100109
Uniprot IDs
O75604
A0A024R1I7
Q9UBB9
PDB IDs
2HD5
2IBI
3NHE
3V6C
3V6E
5XU8
5XVE
6DGF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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