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USP2 and MID2
Data Source:
BioGRID
(two hybrid)
USP2
MID2
Description
ubiquitin specific peptidase 2
midline 2
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Membrane
Perinuclear Region Of Cytoplasm
Cytoplasm
Microtubule
Extracellular Exosome
Molecular Function
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cyclin Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Metal Ion Binding
Transcription Coactivator Activity
Microtubule Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Protein Homodimerization Activity
Phosphoprotein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Muscle Organ Development
Protein Deubiquitination
Protein Phosphopantetheinylation
Circadian Regulation Of Gene Expression
Entrainment Of Circadian Clock By Photoperiod
Locomotor Rhythm
Positive Regulation Of Mitotic Cell Cycle
Circadian Behavior
Protein Stabilization
Positive Regulation Of Autophagy
Protein Ubiquitination
Negative Regulation Of Viral Transcription
Protein Localization To Microtubule
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Viral Release From Host Cell
Pathways
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Ub-specific processing proteases
Regulation of TP53 Degradation
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Serum uric acid levels (
30993211
)
Urate levels (
31985003
31578528
23263486
)
Interacting Genes
163 interacting genes:
ABI2
ACTN1
ACTN2
ACTN3
APP
ASPG
ATN1
AURKA
BAP1
BCAR1
BCL2L2-PABPN1
BEGAIN
BEND5
BHLHB9
BICD2
BIRC7
BRCA1
CADPS
CALCOCO2
CARD9
CBLC
CCDC136
CCDC57
CCDC85B
CCDC88B
CCND1
CEP63
CEP70
CRACR2A
CRACR2B
CRY1
CTNNB1
DDI1
DEPDC5
DISC1
DTX3
DUSP21
DYDC1
EFHC2
EIF4ENIF1
ENPP1
ERBB2
EXOC5
EXOSC8
GEMIN4
GOLGA2
GOLGA6A
GOLGA6L9
GRB7
GRIPAP1
H2AC20
HOMER3
HOOK1
HOOK2
IHO1
IKBKG
IKZF3
IL1RL2
INTS11
JAKMIP1
JRK
KAZN
KIFC3
KRT15
KRT27
KRT31
KRT33B
KRT34
KRT35
KRT40
LHX3
LHX4
LMNA
LMNB2
LNX2
LONRF1
LRSAM1
LZTS2
MALT1
MAP3K2
MDM2
MID2
MNAT1
MORN5
MRPL28
MTUS2
MYC
NAB2
NDEL1
NEFL
NFKB2
NOTCH1
OIP5
OPTN
ORC3
ORC5
PALB2
PCGF6
PCNA
PEX5
PIBF1
PICK1
PIK3R3
PLA2G2A
PLEKHG4
PNMA1
POU2AF1
PRDM14
PRR5L
RABEP1
RAD18
RBCK1
RFX6
RNF125
RNF126
RNF144B
RNF166
RUNDC3A
S100A10
SH2B2
SNCA
SORBS3
SPAG8
SPDYE4
STAT5B
TAX1BP1
TEKT4
TFIP11
TGFBR1
TLE5
TNFAIP2
TRAF1
TRAF2
TRAF6
TRAIP
TRIM21
TRIM23
TRIM27
TRIM34
TRIM35
TRIM39
TRIM46
TRIM5
TRIM50
TRIM54
TRIM63
TRIM74
TRIM8
TRIM9
TRIP6
UBE2S
UBOX5
USHBP1
USP15
USP21
USP54
VCAM1
VPS28
VPS52
ZAP70
ZBED1
ZIM2
ZRANB1
238 interacting genes:
ADAMTSL4
AEN
ALDH3B1
ANKS1A
AP1M1
AQP1
ARHGEF5
ATRIP
AXIN1
BAHD1
BCL6B
BLK
BLZF1
BRCA1
BRMS1L
BYSL
C1orf35
CALCOCO2
CARD9
CARHSP1
CBX8
CCDC120
CCDC185
CCDC187
CCDC33
CCDC42
CCHCR1
CDK18
CEP57L1
CFP
CHD2
CNNM3
COX5B
CPSF4
CRACR2A
CREBRF
CTSZ
DCX
DGCR6
DGCR6L
DMRT3
DYDC1
EFHC2
EGFL7
EIF1AD
ELOA
ENKD1
EPN2
ETNK2
FAM107A
FAM161A
FAM161B
FAM214A
FAM214B
FAM50B
FAM90A1
FARS2
FASTKD5
FBF1
FBXL18
FBXW5
FOXD4L3
FRMD6
FSD2
GAS2L2
GAS8
GCC1
GEM
GFI1B
GMCL1
GOLGA2
GOLGA7
GORASP2
GPANK1
GPKOW
GSC2
HAPLN2
HCK
HDAC4
HDX
HNRNPLL
HOXB2
HOXB5
HOXB9
IGBP1
IGFN1
IHO1
IKZF3
IL16
INO80B
IQCN
ISCU
ITGB4
JOSD1
KANK2
KIF1A
KIF9
KIFC3
KRT27
KRT31
KRT40
KRT75
KRT76
LAGE3
LENG1
LGALS14
LGALS8
LMNB2
LMNTD2
LMO3
LMO4
LNX1
LONRF1
LRRC45
LZTS1
LZTS2
MAGEA6
MAGOHB
MEOX1
MEOX2
METTL17
MFAP1
MID1
MID1IP1
MOS
MVP
NCOA4
NR1D2
NSMF
NXF1
OTUB2
PICK1
PKN1
POLDIP3
PPP1R18
PRDM16
PRPF3
PRPF31
PSMA1
PTCD2
PTPDC1
QARS1
RABGEF1
RANBP3L
RCOR3
REL
RLN1
RNF6
RORB
RPH3AL
RPP25L
RUNX1T1
RXRB
SCNM1
SDCBP
SEPTIN1
SHFL
SLC25A48
SLC25A6
SNAI1
SNAP47
SPAG5
SPATA24
SPG21
SPRY2
STX11
SYNGAP1
SYT17
TASOR2
TBC1D22B
TCAF1
TCEA2
TCEANC
TEKT1
THAP7
TMEM14B
TOP3B
TRIM27
TRIM29
TRIM32
TRIM41
TRIM42
TRIM54
TRIM69
TRPV6
TSGA10
TTC23
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E2
UBE2E3
UBE2K
UBE2U
UBTD1
UNC45A
USP2
USP25
USP54
UTP23
UTP25
WT1-AS
ZBTB16
ZBTB24
ZBTB42
ZC2HC1C
ZFYVE21
ZGPAT
ZIM2
ZNF124
ZNF165
ZNF177
ZNF24
ZNF250
ZNF266
ZNF408
ZNF410
ZNF417
ZNF438
ZNF440
ZNF451
ZNF497
ZNF552
ZNF559-ZNF177
ZNF564
ZNF587
ZNF648
ZNF669
ZNF688
ZNF696
ZNF764
ZNF774
ZNF784
ZNF785
ZNF792
ZRANB1
ZSCAN12
Entrez ID
9099
11043
HPRD ID
05287
02191
Ensembl ID
ENSG00000036672
ENSG00000080561
Uniprot IDs
O75604
Q6GX22
Q9UJV3
PDB IDs
2HD5
2IBI
3NHE
3V6C
3V6E
5XU8
5XVE
6DGF
2DJA
2DMK
Enriched GO Terms of Interacting Partners
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