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PNMA1 and VAV2
Data Source:
BioGRID
(two hybrid)
PNMA1
VAV2
Description
PNMA family member 1
vav guanine nucleotide exchange factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Cytosol
Plasma Membrane
Molecular Function
Protein Binding
Phosphotyrosine Residue Binding
Guanyl-nucleotide Exchange Factor Activity
Epidermal Growth Factor Receptor Binding
Protein Binding
Metal Ion Binding
Biological Process
Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Apoptotic Process
Angiogenesis
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Small GTPase Mediated Signal Transduction
Regulation Of Cell Size
Cell Migration
Lamellipodium Assembly
Platelet Activation
Fc-epsilon Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Apoptotic Process
Regulation Of GTPase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Pathways
GPVI-mediated activation cascade
GPVI-mediated activation cascade
NRAGE signals death through JNK
Rho GTPase cycle
Regulation of actin dynamics for phagocytic cup formation
DAP12 signaling
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
EPH-ephrin mediated repulsion of cells
G alpha (12/13) signalling events
VEGFA-VEGFR2 Pathway
VEGFA-VEGFR2 Pathway
Signal transduction by L1
VEGFR2 mediated vascular permeability
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Central corneal thickness (
29760442
)
Corneal astigmatism (
30306274
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Multiple sclerosis (
20598377
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Red blood cell count (
32888494
)
vWF and FVIII levels (
21810271
)
Interacting Genes
167 interacting genes:
ABHD17A
AGTR1
ANKRD36BP1
APTX
ARHGEF6
ARID5A
ASMTL
ATP5PO
ATP6V1G1
ATXN7
BEX2
BYSL
C1orf109
C21orf58
C8orf33
CARHSP1
CBX8
CCDC146
CCDC187
CCDC198
CCDC33
CCNG1
CCP110
CDK18
CFAP53
CHIC2
CHMP2B
CNNM3
COX5B
CTNNA3
DAXX
DCTN4
EAF2
EHHADH
ENKD1
FAM107A
FAM110A
FAM161A
FAM161B
FBF1
FBXL18
FEM1C
FMNL2
FOXD4L1
FOXD4L3
GADD45GIP1
GATA1
GEM
GPANK1
GPR25
GRAP2
GTPBP10
HAPLN2
HCK
HDAC4
HGS
HNRNPLL
HOXB9
IGFN1
INO80B
IVD
KANSL1
KAT2B
LAGE3
LENG1
LIN37
LMO3
LNX1
LSM2
MAB21L2
MACIR
MARK4
MCM7
MED8
METTL17
MRPL10
MRPL11
MRPL23
MSI1
MYO15B
MYOZ1
NIF3L1
NPBWR2
NSMF
NTAQ1
NUDT16L1
PARD3
PARD6B
PCGF6
PER1
PIN1
PIN4
PKN1
PKN3
PNMA5
PNMA6A
POLDIP3
POLL
POLM
PRKAB2
PRKCG
PRKCI
PRPF18
PRPF31
PSMA1
RAD51D
RAPGEF3
RBM41
RPP25
RPP25L
RSPH9
RSRC2
RTP5
RUSC1
SCAND1
SCNM1
SDCBP
SEMA4C
SH2D4A
SHC3
SHISA3
SLC25A48
SLIRP
SMIM3
SNRPB
SNRPB2
SPATC1L
SPG7
SSX2IP
STAMBPL1
SUV39H2
TASOR2
TCEA2
TCEANC
TCL1B
TEAD4
TMSB4X
TNNI1
TNNT1
TRIM42
TRIM73
TRPV6
TSHZ2
TSPYL4
TTC23
TTC9C
TXNDC9
UBQLN1
UBQLN4
URB1-AS1
USP2
VAV2
VBP1
VPS9D1
WDR25
WT1-AS
ZC2HC1C
ZCCHC12
ZFYVE26
ZG16B
ZNF148
ZNF35
ZNF410
ZNF438
ZNF564
ZNF581
ZNF688
66 interacting genes:
AR
ARIH1
BIRC6
BOD1L1
BRDT
BZW1
CAV1
CBL
CBLB
CCNO
CCT2
CCT3
CD19
CD44
CEP170
CHMP3
CRCP
DCUN1D4
DNAJC21
EGFR
EIF4G3
EPHB2
ERBB2
ERBB3
ERBB4
FNTA
FUCA1
FYN
GAB1
GAPVD1
GRB2
HNRNPF
HSPH1
IPO4
MED21
MET
MRGBP
NCKAP5
NEK3
PHF10
PNMA1
POGZ
PPM1B
PRLR
RAC1
RAD23A
RBBP6
RHOA
RHOG
SERBP1
SF3A3
SH3BP2
SNW1
SOCS1
SRPK2
SRRT
ST13
STK24
SYK
TARBP2
TCP11
TOM1L1
TTN
UBE4B
USP38
VCPIP1
Entrez ID
9240
7410
HPRD ID
04926
02694
Ensembl ID
ENSG00000176903
ENSG00000160293
Uniprot IDs
Q8ND90
P52735
PDB IDs
2DLZ
2DM1
2LNW
2LNX
4ROJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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