Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
RNF8 and UBE2W
Data Source:
BioGRID
(two hybrid)
RNF8
UBE2W
Description
ring finger protein 8
ubiquitin conjugating enzyme E2 W
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Cytosol
Midbody
Site Of Double-strand Break
Nucleus
Nucleoplasm
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Histone Binding
Identical Protein Binding
Protein Homodimerization Activity
Ubiquitin Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Double-strand Break Repair
Double-strand Break Repair Via Nonhomologous End Joining
Ubiquitin-dependent Protein Catabolic Process
Cellular Response To DNA Damage Stimulus
Cell Cycle
Spermatid Development
Response To Ionizing Radiation
Viral Process
Protein Ubiquitination
Histone H2A Ubiquitination
Histone H2B Ubiquitination
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Spermatogenesis, Exchange Of Chromosomal Proteins
Interstrand Cross-link Repair
Histone Exchange
Isotype Switching
Positive Regulation Of DNA Repair
Cell Division
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Histone H2A K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein Polyubiquitination
DNA Repair
Protein Monoubiquitination
Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K11-linked Ubiquitination
Cellular Response To Misfolded Protein
Pathways
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Restless legs syndrome (
29029846
)
Malaria (
31844061
)
Manganese levels (
26025379
)
Urate levels in obese individuals (
25811787
)
Interacting Genes
76 interacting genes:
AMOTL2
BLM
C2CD6
CALCOCO1
CCDC14
CCDC50
CCDC85B
CEP44
CEP85
CHD4
CHEK2
CLK2
CLK3
DNM2
DNTTIP2
EPN2
EPN3
EXOSC2
FAM9B
FSD2
GPRASP2
H2AC20
H2AX
H2BC21
H2BC3
H3-3B
HOMEZ
JMJD1C
KDM4A
KIF24
KRTAP10-1
KRTAP10-8
KRTAP9-2
KRTAP9-8
LMO4
MAD1L1
MAGED1
MAPK1
MDC1
MDM2
PCNA
PCYT1A
PGRMC2
PICK1
PNMA2
POLD4
PSMB1
RBFOX2
RXRA
RYBP
SCN3B
SEPTIN3
SH3GL3
STX11
SUMO2
SUMO3
TMEM79
TNIP1
TOMM20L
TRIM29
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2N
UBE2V2
UBE2W
VCP
WASL
YEATS4
ZBTB10
ZNF346
ZNF496
78 interacting genes:
AKR1C3
AMFR
BARD1
BFAR
BIRC2
BIRC8
BRCA1
CADPS2
CBL
CHFR
CNOT4
DNMT3B
DTX3
DTX3L
DZIP3
EED
FANCL
LRSAM1
MAP3K1
MAPT
MARCHF3
MARCHF5
MGRN1
MIB1
MID1
MKRN1
MKRN3
MUL1
PJA2
POLR2C
PSTPIP1
RFWD3
RMND5B
RNF10
RNF103
RNF111
RNF114
RNF115
RNF123
RNF125
RNF138
RNF14
RNF150
RNF152
RNF165
RNF166
RNF167
RNF183
RNF185
RNF2
RNF26
RNF31
RNF4
RNF5
RNF8
ROPN1
SNCA
STUB1
TOPORS
TRIM17
TRIM2
TRIM21
TRIM23
TRIM27
TRIM31
TRIM35
TRIM39
TRIM5
TRIM59
TRIM8
UBA1
UBOX5
UFM1
UHRF2
USHBP1
XIAP
ZNRF1
ZNRF4
Entrez ID
9025
55284
HPRD ID
11521
07724
Ensembl ID
ENSG00000112130
ENSG00000104343
Uniprot IDs
O76064
Q96B02
Q96FI0
X6REH9
PDB IDs
2CSW
2PIE
4AYC
4ORH
4WHV
2A7L
2MT6
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?