UBE2W and RNF152

Data Source:
BioGRID (two hybrid)

		UBE2W	RNF152
Description		ubiquitin conjugating enzyme E2 W	ring finger protein 152
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Lysosome Lysosomal Membrane Integral Component Of Organelle Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding Small GTPase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Response To Misfolded Protein	Apoptotic Process Positive Regulation Of Autophagy Protein Ubiquitination Cellular Response To Amino Acid Starvation Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of TORC1 Signaling
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Malaria ( 31844061) Manganese levels ( 26025379) Urate levels in obese individuals ( 25811787)	Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372 26831199)
Interacting Genes		78 interacting genes: AKR1C3 AMFR BARD1 BFAR BIRC2 BIRC8 BRCA1 CADPS2 CBL CHFR CNOT4 DNMT3B DTX3 DTX3L DZIP3 EED FANCL LRSAM1 MAP3K1 MAPT MARCHF3 MARCHF5 MGRN1 MIB1 MID1 MKRN1 MKRN3 MUL1 PJA2 POLR2C PSTPIP1 RFWD3 RMND5B RNF10 RNF103 RNF111 RNF114 RNF115 RNF123 RNF125 RNF138 RNF14 RNF150 RNF152 RNF165 RNF166 RNF167 RNF183 RNF185 RNF2 RNF26 RNF31 RNF4 RNF5 RNF8 ROPN1 SNCA STUB1 TOPORS TRIM17 TRIM2 TRIM21 TRIM23 TRIM27 TRIM31 TRIM35 TRIM39 TRIM5 TRIM59 TRIM8 UBA1 UBOX5 UFM1 UHRF2 USHBP1 XIAP ZNRF1 ZNRF4	10 interacting genes: CROCC EBP GJA8 KIR2DL3 RHEB RRAGA TSPAN12 UBE2E1 UBE2N UBE2W
Entrez ID		55284	220441
HPRD ID		07724	11514
Ensembl ID		ENSG00000104343	ENSG00000176641
Uniprot IDs		Q96B02 Q96FI0 X6REH9	Q8N8N0
PDB IDs		2A7L 2MT6
Enriched GO Terms of Interacting Partners?
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