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RNF8 and PNMA2
Data Source:
BioGRID
(two hybrid, two hybrid)
RNF8
PNMA2
Description
ring finger protein 8
PNMA family member 2
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Cytosol
Midbody
Site Of Double-strand Break
Nucleolus
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Histone Binding
Identical Protein Binding
Protein Homodimerization Activity
Ubiquitin Binding
Ubiquitin Protein Ligase Activity
Protein Binding
Biological Process
Double-strand Break Repair
Double-strand Break Repair Via Nonhomologous End Joining
Ubiquitin-dependent Protein Catabolic Process
Cellular Response To DNA Damage Stimulus
Cell Cycle
Spermatid Development
Response To Ionizing Radiation
Viral Process
Protein Ubiquitination
Histone H2A Ubiquitination
Histone H2B Ubiquitination
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Spermatogenesis, Exchange Of Chromosomal Proteins
Interstrand Cross-link Repair
Histone Exchange
Isotype Switching
Positive Regulation Of DNA Repair
Cell Division
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Histone H2A K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Positive Regulation Of Apoptotic Process
Pathways
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Restless legs syndrome (
29029846
)
Brain morphology (MOSTest) (
32665545
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Interacting Genes
76 interacting genes:
AMOTL2
BLM
C2CD6
CALCOCO1
CCDC14
CCDC50
CCDC85B
CEP44
CEP85
CHD4
CHEK2
CLK2
CLK3
DNM2
DNTTIP2
EPN2
EPN3
EXOSC2
FAM9B
FSD2
GPRASP2
H2AC20
H2AX
H2BC21
H2BC3
H3-3B
HOMEZ
JMJD1C
KDM4A
KIF24
KRTAP10-1
KRTAP10-8
KRTAP9-2
KRTAP9-8
LMO4
MAD1L1
MAGED1
MAPK1
MDC1
MDM2
PCNA
PCYT1A
PGRMC2
PICK1
PNMA2
POLD4
PSMB1
RBFOX2
RXRA
RYBP
SCN3B
SEPTIN3
SH3GL3
STX11
SUMO2
SUMO3
TMEM79
TNIP1
TOMM20L
TRIM29
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2N
UBE2V2
UBE2W
VCP
WASL
YEATS4
ZBTB10
ZNF346
ZNF496
32 interacting genes:
BYSL
CBX8
CCDC33
CDC37
CNNM3
ENKD1
FAM161A
GPATCH2L
HAPLN2
INO80B
LRR1
MISP
MORF4L2
NTAQ1
PPIG
PRPF31
PSMA1
RNF6
RNF8
RPL9
RTP5
SCNM1
SDCBP
THAP7
TOP3B
TTLL10
ZNF408
ZNF417
ZNF587
ZNF669
ZNF688
ZNF785
Entrez ID
9025
10687
HPRD ID
11521
04915
Ensembl ID
ENSG00000112130
ENSG00000240694
Uniprot IDs
O76064
Q5U5Z3
Q9UL42
PDB IDs
2CSW
2PIE
4AYC
4ORH
4WHV
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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