HSPB3 and HSPB2

Data Source:
HPRD (in vivo)

		HSPB3	HSPB2
Description		heat shock protein family B (small) member 3	heat shock protein family B (small) member 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck	Nucleus Cytoplasm Cytosol
	Molecular Function		Structural Constituent Of Eye Lens Protein Binding Enzyme Activator Activity
	Biological Process	Response To Unfolded Protein	Response To Unfolded Protein Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Systolic blood pressure (dietary potassium intake interaction) ( 29212900)
Interacting Genes		19 interacting genes: ANP32A BBOX1 HSPB2 HSPB8 LRIF1 LSM14B MED31 MED8 MRPL38 NSMF OLFML3 PRPF4B RAMP3 RBM48 RTL8A SETDB1 TCAP UNC119 ZZEF1	108 interacting genes: A1CF A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BAG3 BEX2 BEX4 BGN BICRAL C1QA CAPZA2 CEP19 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DMPK DUSP1 EEF1A1 EIF4A2 ENKD1 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HOXB9 HSPB3 HSPB8 KANK2 LGALS1 LMO1 LMO3 MAPKAPK5 MB MCCC2 MDH1 MISP MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PATZ1 PGM1 PKP2 POGZ PPM1K PRR35 RFPL3 RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 SNX18 TATDN1 TCAP THEMIS2 THUMPD2 TLX3 TNNI3 TTN TXNIP UBL5 VEZF1 WDR1 WWOX YPEL3 ZNF335
Entrez ID		8988	3316
HPRD ID		06861	03712
Ensembl ID		ENSG00000169271	ENSG00000170276
Uniprot IDs		Q12988 Q6ICS9	A8KAH6 Q16082
PDB IDs		6F2R	6F2R
Enriched GO Terms of Interacting Partners?
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