HSPB3 and PRPF4B

		HSPB3	PRPF4B
Description		heat shock protein family B (small) member 3	pre-mRNA processing factor 4B
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GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck	Nucleus Chromosome Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function		RNA Binding Protein Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Response To Unfolded Protein	MRNA Splicing, Via Spliceosome Protein Phosphorylation RNA Splicing MRNA Cis Splicing, Via Spliceosome
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Systolic blood pressure (dietary potassium intake interaction) ( 29212900)	Night sleep phenotypes ( 27126917)
Interacting Genes		19 interacting genes: ANP32A BBOX1 HSPB2 HSPB8 LRIF1 LSM14B MED31 MED8 MRPL38 NSMF OLFML3 PRPF4B RAMP3 RBM48 RTL8A SETDB1 TCAP UNC119 ZZEF1	8 interacting genes: CLK1 HSPB3 KLF13 PNN POLR3F SRPK2 SRSF1 YWHAG
Entrez ID		8988	8899
HPRD ID		06861	09087
Ensembl ID		ENSG00000169271	ENSG00000112739
Uniprot IDs		Q12988 Q6ICS9	A0A024QZY5 Q13523
PDB IDs		6F2R	4IAN 4IFC 4IIR 4IJP 6CNH 6PJJ 6PK6 6QX9
Enriched GO Terms of Interacting Partners?
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