HSPB2 and MB

Data Source:
BioGRID (two hybrid)

		HSPB2	MB
Description		heat shock protein family B (small) member 2	myoglobin
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytosol Extracellular Exosome
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Enzyme Activator Activity	Oxygen Carrier Activity Oxygen Binding Heme Binding Metal Ion Binding
	Biological Process	Response To Unfolded Protein Regulation Of Catalytic Activity	Response To Hormone Oxygen Transport Slow-twitch Skeletal Muscle Fiber Contraction Response To Hydrogen Peroxide
Pathways			Intracellular oxygen transport
Drugs			Porphyrin Fe(III) N-Butyl Isocyanide Biliverdine IX Alpha Beta-D-Glucose Methylethylamine Tetrazolyl Histidine Nitrosoethane 1-Methylimidazole Imidazole 4-Methylimidazole Ethyl Isocyanide N-Propyl Isocyanide Isocyanomethane Nitrous acid Carbon monoxide
Diseases
GWAS			Triglyceride levels ( 32154731) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		108 interacting genes: A1CF A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BAG3 BEX2 BEX4 BGN BICRAL C1QA CAPZA2 CEP19 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DMPK DUSP1 EEF1A1 EIF4A2 ENKD1 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HOXB9 HSPB3 HSPB8 KANK2 LGALS1 LMO1 LMO3 MAPKAPK5 MB MCCC2 MDH1 MISP MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PATZ1 PGM1 PKP2 POGZ PPM1K PRR35 RFPL3 RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 SNX18 TATDN1 TCAP THEMIS2 THUMPD2 TLX3 TNNI3 TTN TXNIP UBL5 VEZF1 WDR1 WWOX YPEL3 ZNF335	2 interacting genes: APP HSPB2
Entrez ID		3316	4151
HPRD ID		03712	01170
Ensembl ID		ENSG00000170276	ENSG00000198125
Uniprot IDs		A8KAH6 Q16082	A0A1K0FU49 P02144
PDB IDs		6F2R	3RGK
Enriched GO Terms of Interacting Partners?
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