C2CD6 and DNAJA3

Data Source:
BioGRID (two hybrid)

		C2CD6	DNAJA3
Description		C2 calcium dependent domain containing 6	DnaJ heat shock protein family (Hsp40) member A3
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Mitochondrion Mitochondrial Matrix Cytosol Actin Filament Extrinsic Component Of Plasma Membrane Neuromuscular Junction Intracellular Membrane-bounded Organelle Postsynaptic Membrane
	Molecular Function	Protein Binding	Protein Binding ATP Binding Hsp70 Protein Binding GTPase Regulator Activity Metal Ion Binding Unfolded Protein Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Mitochondrial DNA Replication Protein Folding Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Cell Aging Negative Regulation Of Cell Population Proliferation Response To Heat T Cell Differentiation In Thymus Positive Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways
Drugs
Diseases
GWAS			Erectile dysfunction ( 30583798) Immature fraction of reticulocytes ( 32888494) Schizophrenia ( 28991256) Triglyceride levels ( 32203549) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		62 interacting genes: ACOT11 ACTN3 ANKK1 AP2B1 BBS4 BHLHB9 BRCA1 CARD9 CCDC172 CCDC57 CCDC85B CDR2 CHCHD3 CNOT11 CT55 DISC1 DNAJA3 FAM217B FHL2 GOLGA2 GRAMD4 HAP1 HSF2BP HSPB8 IKZF3 JRK KIFC3 KRT13 KRT15 KRT31 KRT40 KRT75 LHX1 LHX3 LZTS2 MCM6 MCRS1 MEAF6 MEOX1 MIPOL1 MTUS2 NR5A1 NUTM1 PAX6 PIBF1 RNF8 SPATA2 TACC3 TCP10L TEX11 TFIP11 TLE5 TRAF1 TRAF2 TRIM23 TRIM54 TSSK3 VAC14 VIM VPS52 ZNF474 ZNRD2	44 interacting genes: ATXN1 BRCA1 C2CD6 CARM1 CIDEB COIL CYSRT1 FAM131C FAM214B FBXO7 FOSL2 FRMD6 GCC1 GFI1B GRB2 HSPA1A HSPA8 IFNGR2 INPP5J JAK2 KDM1A KRAS LAMTOR5 MCPH1 MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 PTEN RAD51 RASA1 RELA RNF34 SMAD9 SMARCB1 STK16 TCF19 USP7 VHL ZBTB22
Entrez ID		151254	9093
HPRD ID		08687	09758
Ensembl ID		ENSG00000155754	ENSG00000103423
Uniprot IDs		A0A140VJE2 Q53TS8	B3KM81 Q53G26 Q59E88 Q96EY1
PDB IDs			2CTT 2DN9 6IWS
Enriched GO Terms of Interacting Partners?
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