ATCAY and KLC1

Data Source:
BioGRID (two hybrid)

		ATCAY	KLC1
Description		ATCAY kinesin light chain interacting caytaxin	kinesin light chain 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Axon Dendrite Growth Cone Mitochondrial Membrane Neuron Projection Neuron Projection Terminus Synapse Perinuclear Region Of Cytoplasm Presynapse	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle
	Molecular Function	Exopolyphosphatase Activity Protein Binding Kinesin Binding	Motor Activity Protein Binding
	Biological Process	Polyphosphate Catabolic Process Apoptotic Process Neuron Projection Development Regulation Of Protein Localization Mitochondrion Distribution Negative Regulation Of Glutamate Metabolic Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases		Cerebellar ataxia cayman type (ATCAY); Cayman ataxia
GWAS		Aging (time to event) ( 21782286)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)
Interacting Genes		5 interacting genes: APP FATE1 KLC1 PIN1 STUB1	28 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CLSTN1 ERBB2 F2RL1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 PTGER4 SNCA SPAG9 TACC3 YWHAB
Entrez ID		85300	3831
HPRD ID		10491	02489
Ensembl ID		ENSG00000167654	ENSG00000126214
Uniprot IDs		A0A0S2Z5T8 Q86WG3	Q07866 Q7RTQ2
PDB IDs			3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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