KLC1 and AP1AR

Data Source:
BioGRID (two hybrid)

		KLC1	AP1AR
Description		kinesin light chain 1	adaptor related protein complex 1 associated regulatory protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle	Endosome Early Endosome Late Endosome Golgi Apparatus Cytosol Transport Vesicle
	Molecular Function	Motor Activity Protein Binding	Kinesin Binding AP-1 Adaptor Complex Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly	Negative Regulation Of Receptor Recycling Protein Transport Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Protein Localization Vesicle Targeting, Trans-Golgi To Endosome Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cell Motility
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)	Body mass index ( 26426971)
Interacting Genes		28 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CLSTN1 ERBB2 F2RL1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 PTGER4 SNCA SPAG9 TACC3 YWHAB	3 interacting genes: AP1G1 GGA1 KLC1
Entrez ID		3831	55435
HPRD ID		02489	12824
Ensembl ID		ENSG00000126214	ENSG00000138660
Uniprot IDs		Q07866 Q7RTQ2	A0A024RDI1 Q63HQ0
PDB IDs		3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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