KLC1 and ATCAY

Data Source:
BioGRID (two hybrid)

		KLC1	ATCAY
Description		kinesin light chain 1	ATCAY kinesin light chain interacting caytaxin
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle	Cytoplasm Mitochondrion Axon Dendrite Growth Cone Mitochondrial Membrane Neuron Projection Neuron Projection Terminus Synapse Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	Motor Activity Protein Binding	Exopolyphosphatase Activity Protein Binding Kinesin Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly	Polyphosphate Catabolic Process Apoptotic Process Neuron Projection Development Regulation Of Protein Localization Mitochondrion Distribution Negative Regulation Of Glutamate Metabolic Process
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases			Cerebellar ataxia cayman type (ATCAY); Cayman ataxia
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)	Aging (time to event) ( 21782286)
Interacting Genes		28 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CLSTN1 ERBB2 F2RL1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 PTGER4 SNCA SPAG9 TACC3 YWHAB	5 interacting genes: APP FATE1 KLC1 PIN1 STUB1
Entrez ID		3831	85300
HPRD ID		02489	10491
Ensembl ID		ENSG00000126214	ENSG00000167654
Uniprot IDs		Q07866 Q7RTQ2	A0A0S2Z5T8 Q86WG3
PDB IDs		3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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