KLC1 and KIF5C

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		KLC1	KIF5C
Description		kinesin light chain 1	kinesin family member 5C
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle	Kinesin Complex Microtubule Dendrite Cytoplasm Ciliary Rootlet Neuronal Cell Body Axonal Growth Cone Distal Axon Axon Cytoplasm
	Molecular Function	Motor Activity Protein Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly	Organelle Organization Microtubule-based Movement Axon Guidance Motor Neuron Axon Guidance Cytoskeleton-dependent Intracellular Transport Synaptic Vesicle Transport MRNA Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Insulin processing
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Chronotype ( 30696823)
Interacting Genes		28 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CLSTN1 ERBB2 F2RL1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 PTGER4 SNCA SPAG9 TACC3 YWHAB	8 interacting genes: CSNK2A1 KIF5A KLC1 KLC3 MEOX2 NCOA2 SNAPIN YWHAG
Entrez ID		3831	3800
HPRD ID		02489	18371
Ensembl ID		ENSG00000126214	ENSG00000168280
Uniprot IDs		Q07866 Q7RTQ2	O60282 Q59GB8
PDB IDs		3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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