Description |
phosphoinositide-3-kinase regulatory subunit 3 |
FYN proto-oncogene, Src family tyrosine kinase |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Body mass index ( 26426971 28448500)
- Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
- Body mass index in physically active individuals ( 28448500)
- Brain morphology (min-P) ( 32665545)
- Brain morphology (MOSTest) ( 32665545)
- Breast cancer ( 29059683)
- Cortical surface area (min-P) ( 32665545)
- Cortical surface area (MOSTest) ( 32665545)
- Cortical thickness (min-P) ( 32665545)
- Cortical thickness (MOSTest) ( 32665545)
- Diastolic blood pressure ( 30224653)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- Estimated glomerular filtration rate ( 31152163)
- Lymphocyte percentage of white cells ( 32888494)
- Metabolite levels ( 23823483)
- Neutrophil count ( 32888494)
- Neutrophil percentage of white cells ( 32888494)
- Red cell distribution width ( 32888494)
- Sodium levels ( 29403010)
- Subcortical volume (min-P) ( 32665545)
- Subcortical volume (MOSTest) ( 32665545)
- Sum neutrophil eosinophil counts ( 27863252)
- White blood cell count ( 32888494 27863252)
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Interacting Genes |
124 interacting genes:
ABCB6
ABL2
AMBP
ANKS1A
ANTKMT
AR
ARID4B
AUNIP
AXL
BLK
BLZF1
BRK1
BTK
C3orf36
C9orf24
CAMK1
CCDC14
CCDC196
CCDC33
CCDC89
CEP126
CEP19
CHRDL2
CLNK
CRBN
CRK
DARS1
DCAF8
DISC1
DRAP1
DSN1
E2F6
EGFR
ENKD1
ERBB2
ERBB3
ERBB4
ESR1
FAM166B
FBN3
FER
FGB
FNDC8
FOXO1
FSD2
FYN
GAB1
GC
GRB2
HROB
HSH2D
IGF1R
INSR
IQUB
IRS1
IRS2
ITGB3BP
KARS1
KHDRBS1
KIAA0408
KIT
KLC2
KLF15
KMT2B
L3MBTL3
LAP3
LNX2
LUC7L2
MBIP
MECOM
MET
MICAL1
MTF2
NAB2
NCK1
NEBL
NEDD9
ORM1
PACRGL
PBX4
PCDHB5
PDGFRB
PELO
PIK3CA
PIK3CD
PLAAT4
PLB1
PLEKHF2
PPARA
PRKAR1B
PSME1
PTK2
QARS1
RB1
RING1
RUSC1
SERF1A
SERTAD2
SOCS6
SPATA32
SRC
SSBP4
STAT3
STAT5B
TASOR2
TEC
TERF2
TNK2
TNNC2
TNNI1
TRIM54
TRMT2A
TSPAN2
USP2
VBP1
VCP
WRNIP1
YES1
YPEL3
ZBTB18
ZMAT1
ZNF281
ZNF451
ZNF620
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198 interacting genes:
ACP1
ADAM15
ADD2
ARHGAP32
ARHGAP33
ATXN1
BAG4
BCAR1
BCL3
BTK
C7orf25
C8orf33
CASP3
CASP8
CAV1
CBL
CBLB
CBLC
CD19
CD2
CD226
CD247
CD2AP
CD36
CD44
CD48
CD5
CD55
CD79A
CD79B
CDH1
CDK1
CDK5
CLTC
CMA1
CNN1
CNN3
CNTN1
CNTNAP1
CRK
CSF1R
CSF2RB
CSK
CTLA4
CTNNB1
CTNND2
DAG1
DLG4
DLGAP4
DOK1
DOK3
DOK4
DTX3
EFS
ENO1
EPHA3
EPHA4
EPHA8
EPHB3
ERRFI1
EVL
FAM90A1
FAS
FASLG
FCER2
FCGR2A
FLOT1
FLOT2
FLT1
FNBP4
FYB1
GAB3
GP6
GRAP
GRB10
GRB2
GRIN1
GRIN2A
GRIN2B
HNRNPK
HRAS
HSP90AA1
HTR6
IGHA1
IL1B
IL2RB
IL7R
IRS1
ITCH
ITGB4
ITK
ITPR1
JAK2
JUP
KDM1A
KDR
KHDRBS1
KIT
LAT
LCK
LCP2
MAG
MAP2
MAPT
MCAM
MED28
MEOX2
MS4A1
NCAM1
NEDD4
NEDD9
NMT1
NOS1AP
NPHS1
NR3C1
NTRK2
PAG1
PAK2
PDE4D
PDGFRB
PECAM1
PIK3R1
PIK3R2
PIK3R3
PLAUR
PLCG1
PLCG2
PLD2
PRKCD
PRKCE
PRKCH
PRKCQ
PRKCZ
PRMT6
PRMT8
PTK2
PTK2B
PTPN11
PTPN5
PTPRA
PTPRC
PTPRE
PTPRF
PTPRZ1
PXN
RACK1
RAF1
RPL10
RPS6KA3
RPS6KB2
SDC3
SH2B2
SH2D1A
SH3BP2
SHC1
SIT1
SKAP1
SKAP2
SLAMF1
SNCA
SOCS1
SOS1
SPHK1
SPHK2
SPN
STAT1
STAT3
SUV39H1
SYK
TAMALIN
TCAP
THY1
TNF
TNK2
TNNT1
TOM1L1
TRAF6
TRAT1
TRIM55
TRIM63
TRPC6
TRPV4
TUBA1B
TUBA3C
TUBA4A
TXK
TYK2
TYRO3
UHRF2
UNC119
VAV1
VAV2
WAS
WASF1
WASF2
WBP11
YTHDC1
ZAP70
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Entrez ID |
8503 |
2534 |
HPRD ID |
05831 |
00655 |
Ensembl ID |
ENSG00000117461
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ENSG00000010810
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Uniprot IDs |
B4DXM8
Q68CY7
Q7Z3W2
Q8N381
Q92569
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P06241
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PDB IDs |
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1A0N
1AOT
1AOU
1AVZ
1AZG
1EFN
1FYN
1G83
1M27
1NYF
1NYG
1SHF
1ZBJ
2DQ7
2MQI
2MRJ
2MRK
3H0F
3H0H
3H0I
3UA6
3UA7
4D8D
4EIK
4U17
4U1P
4ZNX
5ZAU
6EDF
6IPY
6IPZ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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