Description |
phosphoinositide-3-kinase regulatory subunit 3 |
CRK proto-oncogene, adaptor protein |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Body mass index ( 26426971 28448500)
- Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
- Body mass index in physically active individuals ( 28448500)
- Brain morphology (min-P) ( 32665545)
- Brain morphology (MOSTest) ( 32665545)
- Breast cancer ( 29059683)
- Cortical surface area (min-P) ( 32665545)
- Cortical surface area (MOSTest) ( 32665545)
- Cortical thickness (min-P) ( 32665545)
- Cortical thickness (MOSTest) ( 32665545)
- Diastolic blood pressure ( 30224653)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- Estimated glomerular filtration rate ( 31152163)
- Lymphocyte percentage of white cells ( 32888494)
- Metabolite levels ( 23823483)
- Neutrophil count ( 32888494)
- Neutrophil percentage of white cells ( 32888494)
- Red cell distribution width ( 32888494)
- Sodium levels ( 29403010)
- Subcortical volume (min-P) ( 32665545)
- Subcortical volume (MOSTest) ( 32665545)
- Sum neutrophil eosinophil counts ( 27863252)
- White blood cell count ( 32888494 27863252)
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Interacting Genes |
124 interacting genes:
ABCB6
ABL2
AMBP
ANKS1A
ANTKMT
AR
ARID4B
AUNIP
AXL
BLK
BLZF1
BRK1
BTK
C3orf36
C9orf24
CAMK1
CCDC14
CCDC196
CCDC33
CCDC89
CEP126
CEP19
CHRDL2
CLNK
CRBN
CRK
DARS1
DCAF8
DISC1
DRAP1
DSN1
E2F6
EGFR
ENKD1
ERBB2
ERBB3
ERBB4
ESR1
FAM166B
FBN3
FER
FGB
FNDC8
FOXO1
FSD2
FYN
GAB1
GC
GRB2
HROB
HSH2D
IGF1R
INSR
IQUB
IRS1
IRS2
ITGB3BP
KARS1
KHDRBS1
KIAA0408
KIT
KLC2
KLF15
KMT2B
L3MBTL3
LAP3
LNX2
LUC7L2
MBIP
MECOM
MET
MICAL1
MTF2
NAB2
NCK1
NEBL
NEDD9
ORM1
PACRGL
PBX4
PCDHB5
PDGFRB
PELO
PIK3CA
PIK3CD
PLAAT4
PLB1
PLEKHF2
PPARA
PRKAR1B
PSME1
PTK2
QARS1
RB1
RING1
RUSC1
SERF1A
SERTAD2
SOCS6
SPATA32
SRC
SSBP4
STAT3
STAT5B
TASOR2
TEC
TERF2
TNK2
TNNC2
TNNI1
TRIM54
TRMT2A
TSPAN2
USP2
VBP1
VCP
WRNIP1
YES1
YPEL3
ZBTB18
ZMAT1
ZNF281
ZNF451
ZNF620
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169 interacting genes:
ABL1
ABL2
ANKZF1
ANLN
AR
ARHGAP17
ARHGAP32
ASAP1
ASAP3
ASCL4
ATF3
ATXN1
AVIL
BATF3
BCAR1
BCR
BEX5
BUB1
C1orf94
C4orf17
C6orf141
CBL
CBLB
CBLC
CHTF18
CLNK
CNDP2
CORO6
CRKL
DAB1
DOCK1
DOCK3
DOK1
DOK2
DOK3
DOK4
DOK7
DPPA4
EFS
EGFR
ELK1
ELK3
EPHA3
EPHB2
EPHB3
EPHB6
EPS15
EPYC
ERBB2
ERBB3
ERBB4
ESD
EYA3
FASLG
FER
FGFR1
FLACC1
FLT1
FRS2
FSTL1
FYN
GAB1
GABPB2
GAREM1
GRB2
HABP4
HSH2D
IFT140
IGF1R
IKZF3
INO80E
INSR
IRS1
IRS2
IRS4
ISL1
KCTD13
KCTD17
KDR
KHDRBS1
KIT
KLF15
KLHL20
LASP1
LHX8
LNX2
MAGEC3
MAP4K1
MAP4K5
MAPK4
MAPK8
MET
MICAL1
MNDA
MPG
MYLIP
MYOZ2
NCK1
NEDD9
NTRK1
NUFIP2
OFCC1
PAFAH1B2
PDGFRA
PDGFRB
PHC2
PIK3R1
PIK3R2
PIK3R3
PLSCR1
POT1
PPFIBP2
PPP1CA
PRKACA
PRRC2B
PRRG2
PSMC1
PSMC6
PTK2
PTK2B
PTPN1
PTPN4
PTPRH
PTTG1
PXN
RAB2B
RAPGEF1
REPS1
RET
RIN3
RTCB
RYBP
SASH1
SAXO1
SEMA4D
SEPTIN6
SETD9
SH2D2A
SH3BP1
SHB
SHC1
SOCS1
SOCS6
SOS1
SPRR2A
STAT4
STAT5A
STAT5B
STRN4
SYN1
TCAP
TDG
TERF2IP
TM4SF19
TP53
TP53BP2
TUBA1C
TWIST2
TXK
USP53
VAC14
VAV1
WASF1
WDR83
WEE1
XPO1
ZAP70
ZKSCAN7
ZNF557
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Entrez ID |
8503 |
1398 |
HPRD ID |
05831 |
01267 |
Ensembl ID |
ENSG00000117461
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ENSG00000167193
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Uniprot IDs |
B4DXM8
Q68CY7
Q7Z3W2
Q8N381
Q92569
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A0A0S2Z3K9
A0A0S2Z3Q4
L7RT18
P46108
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PDB IDs |
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1JU5
2DVJ
2EYV
2EYW
2EYX
2EYY
2EYZ
2MS4
5UL6
6ATV
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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