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PPM1D and LYPD3
Data Source:
BioGRID
(two hybrid)
PPM1D
LYPD3
Description
protein phosphatase, Mg2+/Mn2+ dependent 1D
LY6/PLAUR domain containing 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Extracellular Region
Extracellular Space
Plasma Membrane
Integral Component Of Membrane
Anchored Component Of Plasma Membrane
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Serine/threonine Phosphatase Activity
Protein Binding
Metal Ion Binding
Mitogen-activated Protein Kinase Binding
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
Laminin Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
DNA Methylation
Chromatin Silencing
Transcription Initiation From RNA Polymerase II Promoter
Protein Phosphorylation
Protein Dephosphorylation
Negative Regulation Of Cell Population Proliferation
Cellular Response To Starvation
Response To Radiation
Response To Bacterium
DNA Damage Response, Signal Transduction By P53 Class Mediator
Peptidyl-threonine Dephosphorylation
Negative Regulation Of Gene Expression, Epigenetic
Cell-matrix Adhesion
Pathways
Transcriptional regulation by RUNX2
Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS
Blood urea nitrogen levels (
31152163
)
Cotinine glucuronidation (
25293881
)
Interacting Genes
24 interacting genes:
BEX2
CASZ1
CHEK2
DIRAS3
DKK3
EPSTI1
ERRFI1
GLCE
H3-3A
H3C1
ITIH5
KDM1A
LYPD3
MAPK11
MDM2
MRC2
NAT2
NCL
NSD3
OSGIN1
RHOBTB2
RPL5
TP53
UBC
17 interacting genes:
AGR2
AGR3
AURKA
BAG4
BRMS1
CASP8
CHEK2
CTRB1
ERBB2
IGF1R
LSP1
PALB2
PPM1D
PTPRJ
RB1CC1
SMAD4
STK11
Entrez ID
8493
27076
HPRD ID
05482
10783
Ensembl ID
ENSG00000170836
ENSG00000124466
Uniprot IDs
A0A0S2Z4M2
O15297
B2RBR3
O95274
PDB IDs
6IOM
6ION
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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