LYPD3 and CTRB1

Data Source:
HPRD (in vitro)

		LYPD3	CTRB1
Description		LY6/PLAUR domain containing 3	chymotrypsinogen B1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Laminin Binding	Serine-type Endopeptidase Activity
	Biological Process	Cell-matrix Adhesion	Proteolysis Digestion Cobalamin Metabolic Process Extracellular Matrix Disassembly
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Activation of Matrix Metalloproteinases Cobalamin (Cbl, vitamin B12) transport and metabolism
Drugs			Trans-O-Hydroxy-Alpha-Methyl Cinnamate 2,4-Dihydroxy-Trans Cinnamic Acid Phenylethane Boronic Acid Phosphorylisopropane Aprotinin 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acid 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE (2S) N-acetyl-L-alanyl-Î±L-phenylalanyl-chloroethylketone 1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) Phenylalanylmethylchloride L-1-naphthyl-2-acetamido-ethane boronic acid D-1-naphthyl-2-acetamido-ethane boronic acid D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid
Diseases
GWAS		Cotinine glucuronidation ( 25293881)	Advanced age-related macular degeneration ( 26691988) Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 29875488) Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Pancreatic cancer ( 25086665) Type 2 diabetes ( 30054458)
Interacting Genes		17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11	4 interacting genes: LYPD3 SERPINA1 SERPINA3 SERPINF2
Entrez ID		27076	1504
HPRD ID		10783	00345
Ensembl ID		ENSG00000124466	ENSG00000168925
Uniprot IDs		B2RBR3 O95274	P17538
PDB IDs		6IOM 6ION
Enriched GO Terms of Interacting Partners?
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