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MAP1LC3A and DVL2
Data Source:
BioGRID
(pull down)
MAP1LC3A
DVL2
Description
microtubule associated protein 1 light chain 3 alpha
dishevelled segment polarity protein 2
Image
GO Annotations
Cellular Component
Autophagosome Membrane
Late Endosome
Autophagosome
Cytosol
Microtubule
Organelle Membrane
Intracellular Membrane-bounded Organelle
Autolysosome
Synapse
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Aggresome
Lateral Plasma Membrane
Nuclear Body
Cytoplasmic Vesicle
Apical Part Of Cell
Clathrin-coated Endocytic Vesicle
Molecular Function
Protein Binding
Phospholipid Binding
Microtubule Binding
Phosphatidylethanolamine Binding
Ubiquitin Protein Ligase Binding
Frizzled Binding
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Protein-macromolecule Adaptor Activity
Small GTPase Binding
Identical Protein Binding
Protein Self-association
Biological Process
Autophagosome Assembly
Autophagy Of Mitochondrion
Cellular Response To Nitrogen Starvation
Cellular Response To Starvation
Response To Iron(II) Ion
Response To Lead Ion
Macroautophagy
Cellular Response To Amino Acid Starvation
Response To Morphine
Cellular Response To Hydrogen Peroxide
Cellular Response To Copper Ion
Autophagosome Maturation
Neural Tube Closure
Positive Regulation Of Protein Phosphorylation
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Segment Specification
Heart Development
Convergent Extension Involved In Neural Plate Elongation
Cellular Protein Localization
Hippo Signaling
Non-canonical Wnt Signaling Pathway
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Membrane Organization
Positive Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Canonical Wnt Signaling Pathway
Cochlea Morphogenesis
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Beta-catenin Destruction Complex Disassembly
Pathways
Macroautophagy
PINK1-PRKN Mediated Mitophagy
Receptor Mediated Mitophagy
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
Signaling by Hippo
PCP/CE pathway
PCP/CE pathway
Asymmetric localization of PCP proteins
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
WNT5A-dependent internalization of FZD4
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Colorectal cancer or advanced adenoma (
30510241
)
Fish- and plant-related diet (
32066663
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Metabolite levels (
31628463
)
Metabolite levels (small molecules and protein measures) (
27005778
)
Interacting Genes
54 interacting genes:
AKAP13
AMBRA1
ANK2
ANK3
APP
ATG13
ATG4B
ATG7
ATXN3
BNIP3L
DVL2
EPHA7
FUNDC1
GPSM1
IRGQ
KIF15
KXD1
LMNB1
MAP1A
MAP1S
MDM2
MEFV
MREG
NBR1
NEDD4
OPRM1
OPTN
PIAS4
PRPF40A
RABGAP1
RABGAP1L
RDH12
RETREG3
RTKN
SQSTM1
SRPK1
TBC1D1
TBC1D10A
TBC1D10B
TBC1D16
TBC1D17
TBC1D2
TBC1D25
TBC1D2B
TBC1D5
TBC1D7
TBC1D9
TBC1D9B
TNIP1
TP53INP1
TRIM21
TRIM32
TUBA4A
VPS9D1
103 interacting genes:
ABL1
AKAP9
AP1M1
AP2M1
ARHGEF39
ARR3
ARRB1
ARRB2
ATN1
AXIN1
BAG3
BAHD1
BCL6
BEND7
BYSL
CARD9
CCDC33
CPSF7
CSNK1E
CTBP2
DAAM1
DCUN1D1
DDI1
DPPA2
DYNLT1
EIF1B
ELOA2
ENKD1
FAM161A
FAM90A1
FZD4
GABARAP
GABARAPL1
GMCL2
GOLGA2
GRAP2
GRB2
HIP1
IHO1
KLHL12
LMO3
LRRK2
MAGOHB
MAP1LC3A
MCRS1
NOL12
NUP62CL
OTULIN
PARD6A
PCBD1
PLA2G12A
POLI
PPM1A
PPP1R16B
PRKAA1
PRKCA
PRKCB
PRKCG
PRPF3
PRPF31
PSMF1
RAC1
RBFOX1
RBPMS
RHOA
RHOXF2
RNF185
RNPS1
RUNX2
RUSC1
SCNM1
SMURF1
SNF8
SNIP1
SORBS3
SSX2IP
TAB1
TDP2
THAP1
TIFA
TLE5
TP53
TPM3
TRAF2
U2AF2
UBAC1
UBE2D3
UIMC1
USP5
USP9X
VANGL1
VHL
WAS
WT1
YES1
ZBTB48
ZBTB8A
ZGPAT
ZNF165
ZNF250
ZNF263
ZNF410
ZNF581
Entrez ID
84557
1856
HPRD ID
03144
03690
Ensembl ID
ENSG00000101460
ENSG00000004975
Uniprot IDs
Q9H492
O14641
PDB IDs
3ECI
3WAL
3WAN
4ZDV
5CX3
5DPR
2REY
3CBX
3CBY
3CBZ
3CC0
4WIP
5LNP
5SUY
5SUZ
6IW3
6JCK
Enriched GO Terms of Interacting Partners
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