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MAP1LC3A and TRIM21
Data Source:
BioGRID
(pull down)
MAP1LC3A
TRIM21
Description
microtubule associated protein 1 light chain 3 alpha
tripartite motif containing 21
Image
GO Annotations
Cellular Component
Autophagosome Membrane
Late Endosome
Autophagosome
Cytosol
Microtubule
Organelle Membrane
Intracellular Membrane-bounded Organelle
Autolysosome
Synapse
P-body
Nucleus
Nucleoplasm
Cytoplasm
Autophagosome
Cytosol
SCF Ubiquitin Ligase Complex
Cytoplasmic Vesicle
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Phospholipid Binding
Microtubule Binding
Phosphatidylethanolamine Binding
Ubiquitin Protein Ligase Binding
DNA Binding
Transcription Coactivator Activity
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Biological Process
Autophagosome Assembly
Autophagy Of Mitochondrion
Cellular Response To Nitrogen Starvation
Cellular Response To Starvation
Response To Iron(II) Ion
Response To Lead Ion
Macroautophagy
Cellular Response To Amino Acid Starvation
Response To Morphine
Cellular Response To Hydrogen Peroxide
Cellular Response To Copper Ion
Autophagosome Maturation
Protein Polyubiquitination
Protein Monoubiquitination
Cell Cycle
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Protein Ubiquitination
Protein Destabilization
Negative Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Protein Binding
Regulation Of Type I Interferon Production
Regulation Of Protein Localization
Negative Regulation Of Viral Transcription
Response To Interferon-gamma
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Positive Regulation Of Cell Cycle
Negative Regulation Of Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Interferon-gamma-mediated Signaling Pathway
Protein K63-linked Ubiquitination
Negative Regulation Of Protein Deubiquitination
Negative Regulation Of Viral Release From Host Cell
Pathways
Macroautophagy
PINK1-PRKN Mediated Mitophagy
Receptor Mediated Mitophagy
STING mediated induction of host immune responses
Regulation of innate immune responses to cytosolic DNA
Interferon gamma signaling
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Colorectal cancer or advanced adenoma (
30510241
)
Fish- and plant-related diet (
32066663
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Lung cancer (
28604730
)
Malaria (
31844061
)
Interacting Genes
54 interacting genes:
AKAP13
AMBRA1
ANK2
ANK3
APP
ATG13
ATG4B
ATG7
ATXN3
BNIP3L
DVL2
EPHA7
FUNDC1
GPSM1
IRGQ
KIF15
KXD1
LMNB1
MAP1A
MAP1S
MDM2
MEFV
MREG
NBR1
NEDD4
OPRM1
OPTN
PIAS4
PRPF40A
RABGAP1
RABGAP1L
RDH12
RETREG3
RTKN
SQSTM1
SRPK1
TBC1D1
TBC1D10A
TBC1D10B
TBC1D16
TBC1D17
TBC1D2
TBC1D25
TBC1D2B
TBC1D5
TBC1D7
TBC1D9
TBC1D9B
TNIP1
TP53INP1
TRIM21
TRIM32
TUBA4A
VPS9D1
71 interacting genes:
ALOX15B
APC
CALR
CASP8AP2
CBX4
CDC34
CUL1
CWC25
DAXX
DCP2
DMAP1
DZIP3
EHHADH
EXOC8
FADD
FBXW11
FHOD1
GABARAP
GABARAPL1
GABARAPL2
GMCL1
GRAP
HLA-DRB1
IGFN1
IGHG1
IGHV4-31
IKBKB
IRF5
IRF8
LNX1
MAP1LC3A
MAP1LC3B
MAP1LC3C
MNAT1
NIF3L1
PFKP
RBCK1
RNF111
RO60
SAMHD1
SETD7
SKP2
SQSTM1
TBK1
TCP11L1
TNS4
TRIM27
TRIM3
TRIM39
TRIM5
TRIM8
TXN2
UBC
UBE2C
UBE2D1
UBE2D2
UBE2E1
UBE2H
UBE2I
UBE2L3
UBE2N
UBE2V2
UBE2W
USP15
USP2
USP4
VPS9D1
XAF1
YJU2
YWHAZ
ZBTB16
Entrez ID
84557
6737
HPRD ID
03144
00170
Ensembl ID
ENSG00000101460
ENSG00000132109
Uniprot IDs
Q9H492
P19474
PDB IDs
3ECI
3WAL
3WAN
4ZDV
5CX3
5DPR
2IWG
5JPX
5OLM
6FGA
6S53
Enriched GO Terms of Interacting Partners
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