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MAP1LC3A and TUBA4A
Data Source:
HPRD
(in vitro)
MAP1LC3A
TUBA4A
Description
microtubule associated protein 1 light chain 3 alpha
tubulin alpha 4a
Image
No pdb structure
GO Annotations
Cellular Component
Autophagosome Membrane
Late Endosome
Autophagosome
Cytosol
Microtubule
Organelle Membrane
Intracellular Membrane-bounded Organelle
Autolysosome
Synapse
Extracellular Region
Cytoplasm
Cytosol
Cytoskeleton
Microtubule
Microtubule Cytoskeleton
Extracellular Exosome
Molecular Function
Protein Binding
Phospholipid Binding
Microtubule Binding
Phosphatidylethanolamine Binding
Ubiquitin Protein Ligase Binding
GTPase Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Protein Kinase Binding
Biological Process
Autophagosome Assembly
Autophagy Of Mitochondrion
Cellular Response To Nitrogen Starvation
Cellular Response To Starvation
Response To Iron(II) Ion
Response To Lead Ion
Macroautophagy
Cellular Response To Amino Acid Starvation
Response To Morphine
Cellular Response To Hydrogen Peroxide
Cellular Response To Copper Ion
Autophagosome Maturation
G2/M Transition Of Mitotic Cell Cycle
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Platelet Degranulation
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Ciliary Basal Body-plasma Membrane Docking
Pathways
Macroautophagy
PINK1-PRKN Mediated Mitophagy
Receptor Mediated Mitophagy
Platelet degranulation
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Cilium Assembly
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
Drugs
Vincristine
Podofilox
Epothilone D
Patupilone
CYT997
Cabazitaxel
Phenethyl Isothiocyanate
Diseases
GWAS
Bipolar disorder (
31043756
)
Colorectal cancer or advanced adenoma (
30510241
)
Fish- and plant-related diet (
32066663
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Platelet distribution width (
32888494
27863252
)
Interacting Genes
54 interacting genes:
AKAP13
AMBRA1
ANK2
ANK3
APP
ATG13
ATG4B
ATG7
ATXN3
BNIP3L
DVL2
EPHA7
FUNDC1
GPSM1
IRGQ
KIF15
KXD1
LMNB1
MAP1A
MAP1S
MDM2
MEFV
MREG
NBR1
NEDD4
OPRM1
OPTN
PIAS4
PRPF40A
RABGAP1
RABGAP1L
RDH12
RETREG3
RTKN
SQSTM1
SRPK1
TBC1D1
TBC1D10A
TBC1D10B
TBC1D16
TBC1D17
TBC1D2
TBC1D25
TBC1D2B
TBC1D5
TBC1D7
TBC1D9
TBC1D9B
TNIP1
TP53INP1
TRIM21
TRIM32
TUBA4A
VPS9D1
51 interacting genes:
APC
ARHGAP1
B4GALT1
BCAR1
BRCA1
C4orf17
CALB2
EGFR
ENO2
EPB41
FYN
GNAI2
GPHN
GRM7
HDAC6
HSPH1
LGALS2
LTA
MAGED1
MAP1A
MAP1LC3A
MAPT
MARK4
MYC
NCALD
PFDN4
PLK1
PRKN
RAB8B
RAC1
RACGAP1
RBM23
RTN4
S100A8
SIAH1
SIMC1
SIRT2
STARD13
SUMO2
SYK
TAOK2
TBCB
TBCE
TCP1
TCP11L2
TM4SF1
UCHL5
VAV1
VDAC1
YWHAG
ZAP70
Entrez ID
84557
7277
HPRD ID
03144
01851
Ensembl ID
ENSG00000101460
ENSG00000127824
Uniprot IDs
Q9H492
P68366
PDB IDs
3ECI
3WAL
3WAN
4ZDV
5CX3
5DPR
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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