MAP1LC3A and AMBRA1

  • Data Source:
  • BioGRID (unspecified method, affinity chromatography technology)

MAP1LC3A

AMBRA1

Description microtubule associated protein 1 light chain 3 alpha autophagy and beclin 1 regulator 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 28552196)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Immunoglobulin A ( 20694011)
  • Insulin-related traits (multivariate analysis) ( 32002517)
  • Normal facial asymmetry (angle of deformation score) ( 30631343)
  • Schizophrenia ( 28991256 29483656 30285260)
  • Selective IgA deficiency ( 27723758)
Interacting Genes 54 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG13 ATG4B ATG7 ATXN3 BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 IRGQ KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV MREG NBR1 NEDD4 OPRM1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RETREG3 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TRIM32 TUBA4A VPS9D1 12 interacting genes: BECN1 CHUK GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C MTOR RNF2 SNCA UBE2D3
Entrez ID 84557 55626
HPRD ID 03144 10975
Ensembl ID ENSG00000101460 ENSG00000110497
Uniprot IDs Q9H492 A0A075B6T1 Q9C0C7
PDB IDs 3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?