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JAGN1 and VAPB
Data Source:
BioGRID
(two hybrid)
JAGN1
VAPB
Description
jagunal homolog 1
VAMP associated protein B and C
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Golgi Membrane
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Plasma Membrane
Integral Component Of Membrane
Endoplasmic Reticulum Exit Site
Molecular Function
Protein Binding
Protein Binding
Microtubule Binding
Enzyme Binding
FFAT Motif Binding
Protein Homodimerization Activity
Cadherin Binding
Protein Heterodimerization Activity
Beta-tubulin Binding
Biological Process
Neutrophil Mediated Immunity
Exocytosis
Endoplasmic Reticulum Organization
Protein Transport
Vesicle-mediated Transport
Neutrophil Differentiation
Granulocyte Colony-stimulating Factor Signaling Pathway
Defense Response To Fungus
Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Cellular Response To Tunicamycin
Neutrophil Migration
Cellular Calcium Ion Homeostasis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Endoplasmic Reticulum Organization
Modulation By Virus Of Host Process
Sphingolipid Biosynthetic Process
Endoplasmic Reticulum Unfolded Protein Response
IRE1-mediated Unfolded Protein Response
Positive Regulation Of Viral Genome Replication
Endoplasmic Reticulum-plasma Membrane Tethering
COPII-coated Vesicle Budding
Endoplasmic Reticulum Membrane Organization
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS
Interacting Genes
126 interacting genes:
AGPAT4
APP
AQP6
ARL13B
BCL2L13
BET1
BMP10
BNIP1
BNIP3
BSND
BTNL9
C4orf3
CALHM6
CCL4L2
CD79A
CDIPT
CERS4
CGRRF1
CLDN7
CLEC12B
CLEC4D
CLEC7A
CMTM5
COX20
CREB3L1
CYBC1
CYP4F2
DNAJC30
EBP
EDA2R
EHHADH
ELOVL4
ERG28
ERGIC3
F11R
FAM177A1
FAM209A
FCGR1A
FCRL2
FCRL4
FDFT1
FIS1
FKBP8
FNDC9
FRMD3
FXYD6
GIMAP1
GIMAP5
GJB5
GOLM1
GOSR2
GP2
GPR152
GPR37L1
HMOX1
HSD17B13
HTATIP2
ICMT
IER3IP1
IFNGR2
IL3RA
KASH5
KCNA1
KIR2DL3
KIR3DL3
LEMD1
LHFPL5
LMNA
LPAR3
MFF
MRM3
MTIF3
NINJ2
NRG1
OTULINL
PDZK1IP1
PLP1
PLPP2
PSCA
RETREG3
RTP2
SACM1L
SAR1A
SCD
SEC22B
SERP1
SLAMF6
SLC16A2
SLC23A2
SLC34A2
SMAGP
SMIM1
SMIM19
STOML3
STX1A
STX3
STX5
STX7
STX8
TECR
TIMM23
TMEM100
TMEM106C
TMEM120B
TMEM128
TMEM14B
TMEM199
TMEM207
TMEM237
TMEM242
TMEM243
TMEM52B
TMEM65
TMIE
TNFSF14
TREX1
TSNARE1
UBE2J1
USE1
VAMP2
VAMP5
VAPA
VAPB
VKORC1
VSIG4
VTI1B
41 interacting genes:
AIG1
AQP2
AQP6
CD79A
CYB561
CYBRD1
EBAG9
EBP
ELOVL4
EMD
FAM174A
GLP1R
GPR25
HSD17B13
JAGN1
KCNB1
MTNR1A
OSBPL2
PTGES
REEP4
RETREG3
RMDN2
RNASEK
RNF111
SCN3B
SLC22A1
SLC35C2
STX1A
STX2
STX4
STX5
TMEM101
TMX2
TTC39B
USP20
VAMP1
VAMP2
VHL
VKORC1
ZBTB22
ZDHHC15
Entrez ID
84522
9217
HPRD ID
13749
09300
Ensembl ID
ENSG00000171135
ENSG00000124164
Uniprot IDs
Q8N5M9
O95292
Q53XM7
PDB IDs
2MDK
3IKK
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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