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VAPB and STX2
Data Source:
BioGRID
(pull down)
VAPB
STX2
Description
VAMP associated protein B and C
syntaxin 2
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Plasma Membrane
Integral Component Of Membrane
Endoplasmic Reticulum Exit Site
Extracellular Space
Plasma Membrane
Synaptic Vesicle
Endomembrane System
Integral Component Of Membrane
Basolateral Plasma Membrane
Lamellipodium
SNARE Complex
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Presynaptic Active Zone Membrane
Molecular Function
Protein Binding
Microtubule Binding
Enzyme Binding
FFAT Motif Binding
Protein Homodimerization Activity
Cadherin Binding
Protein Heterodimerization Activity
Beta-tubulin Binding
SNARE Binding
Structural Molecule Activity
SNAP Receptor Activity
Protein Binding
Calcium-dependent Protein Binding
Biological Process
Cellular Calcium Ion Homeostasis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Endoplasmic Reticulum Organization
Modulation By Virus Of Host Process
Sphingolipid Biosynthetic Process
Endoplasmic Reticulum Unfolded Protein Response
IRE1-mediated Unfolded Protein Response
Positive Regulation Of Viral Genome Replication
Endoplasmic Reticulum-plasma Membrane Tethering
COPII-coated Vesicle Budding
Endoplasmic Reticulum Membrane Organization
Intracellular Protein Transport
Exocytosis
Vesicle Fusion
Signal Transduction
Acrosome Reaction
Ectoderm Development
Animal Organ Morphogenesis
Cell Differentiation
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Cellular Response To Oxidative Stress
Vesicle Docking
Cornified Envelope Assembly
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS
Initial pursuit acceleration in psychotic disorders (
29064472
)
Metabolite levels (
23823483
)
Plasma plasminogen activator levels (
24578379
)
vWF levels (
30586737
)
Interacting Genes
41 interacting genes:
AIG1
AQP2
AQP6
CD79A
CYB561
CYBRD1
EBAG9
EBP
ELOVL4
EMD
FAM174A
GLP1R
GPR25
HSD17B13
JAGN1
KCNB1
MTNR1A
OSBPL2
PTGES
REEP4
RETREG3
RMDN2
RNASEK
RNF111
SCN3B
SLC22A1
SLC35C2
STX1A
STX2
STX4
STX5
TMEM101
TMX2
TTC39B
USP20
VAMP1
VAMP2
VHL
VKORC1
ZBTB22
ZDHHC15
64 interacting genes:
AARD
ABI3
ANKRD46
APOL2
BET1
BLOC1S2
CD53
CDC23
CERT1
CPLX2
CTSA
CYBC1
EBAG9
ENTPD3
FGA
GET1
GIMAP5
MIP
MRPL11
MTG1
NAPB
NINJ2
PCGF2
PLN
PLPP4
RMDN3
RNF4
RTP2
SEC22A
SEC22B
SERP1
SLC18A1
SNAP25
SNAP29
STRIT1
STX12
STX16
STX1A
STX1B
STX3
STX4
STX5
STX6
STX7
STX8
STXBP1
STXBP2
STXBP5L
SYT1
SYT4
SYT7
TMEM120A
TMEM120B
TSPAN8
UBE2I
UNC13B
VAMP2
VAMP3
VAMP5
VAPB
VTI1B
ZCCHC12
ZFPL1
ZNF785
Entrez ID
9217
2054
HPRD ID
09300
11816
Ensembl ID
ENSG00000124164
ENSG00000111450
Uniprot IDs
O95292
Q53XM7
P32856
PDB IDs
2MDK
3IKK
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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