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JAGN1 and ICMT
Data Source:
BioGRID
(two hybrid)
JAGN1
ICMT
Description
jagunal homolog 1
isoprenylcysteine carboxyl methyltransferase
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Protein C-terminal Carboxyl O-methyltransferase Activity
Protein C-terminal S-isoprenylcysteine Carboxyl O-methyltransferase Activity
Protein Binding
Biological Process
Neutrophil Mediated Immunity
Exocytosis
Endoplasmic Reticulum Organization
Protein Transport
Vesicle-mediated Transport
Neutrophil Differentiation
Granulocyte Colony-stimulating Factor Signaling Pathway
Defense Response To Fungus
Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Cellular Response To Tunicamycin
Neutrophil Migration
Cellular Protein Modification Process
C-terminal Protein Methylation
Protein Targeting To Membrane
Post-translational Protein Modification
Pathways
Gamma carboxylation, hypusine formation and arylsulfatase activation
RAS processing
Drugs
Diseases
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Resting heart rate (
27798624
28270201
)
Interacting Genes
126 interacting genes:
AGPAT4
APP
AQP6
ARL13B
BCL2L13
BET1
BMP10
BNIP1
BNIP3
BSND
BTNL9
C4orf3
CALHM6
CCL4L2
CD79A
CDIPT
CERS4
CGRRF1
CLDN7
CLEC12B
CLEC4D
CLEC7A
CMTM5
COX20
CREB3L1
CYBC1
CYP4F2
DNAJC30
EBP
EDA2R
EHHADH
ELOVL4
ERG28
ERGIC3
F11R
FAM177A1
FAM209A
FCGR1A
FCRL2
FCRL4
FDFT1
FIS1
FKBP8
FNDC9
FRMD3
FXYD6
GIMAP1
GIMAP5
GJB5
GOLM1
GOSR2
GP2
GPR152
GPR37L1
HMOX1
HSD17B13
HTATIP2
ICMT
IER3IP1
IFNGR2
IL3RA
KASH5
KCNA1
KIR2DL3
KIR3DL3
LEMD1
LHFPL5
LMNA
LPAR3
MFF
MRM3
MTIF3
NINJ2
NRG1
OTULINL
PDZK1IP1
PLP1
PLPP2
PSCA
RETREG3
RTP2
SACM1L
SAR1A
SCD
SEC22B
SERP1
SLAMF6
SLC16A2
SLC23A2
SLC34A2
SMAGP
SMIM1
SMIM19
STOML3
STX1A
STX3
STX5
STX7
STX8
TECR
TIMM23
TMEM100
TMEM106C
TMEM120B
TMEM128
TMEM14B
TMEM199
TMEM207
TMEM237
TMEM242
TMEM243
TMEM52B
TMEM65
TMIE
TNFSF14
TREX1
TSNARE1
UBE2J1
USE1
VAMP2
VAMP5
VAPA
VAPB
VKORC1
VSIG4
VTI1B
12 interacting genes:
AQP6
ARL13B
HRAS
JAGN1
KCNJ6
MUC1
PDZK1IP1
RAC1
RAC2
RHOA
RNF19B
TRIM32
Entrez ID
84522
23463
HPRD ID
13749
09321
Ensembl ID
ENSG00000171135
ENSG00000116237
Uniprot IDs
Q8N5M9
A0A024R4F6
B3KS61
O60725
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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