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VAPB and CYB561
Data Source:
BioGRID
(two hybrid)
VAPB
CYB561
Description
VAMP associated protein B and C
cytochrome b561
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Plasma Membrane
Integral Component Of Membrane
Endoplasmic Reticulum Exit Site
Lysosomal Membrane
Integral Component Of Membrane
Transport Vesicle Membrane
Molecular Function
Protein Binding
Microtubule Binding
Enzyme Binding
FFAT Motif Binding
Protein Homodimerization Activity
Cadherin Binding
Protein Heterodimerization Activity
Beta-tubulin Binding
Ferric-chelate Reductase Activity
Protein Binding
Oxidoreductase Activity
Metal Ion Binding
Biological Process
Cellular Calcium Ion Homeostasis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Endoplasmic Reticulum Organization
Modulation By Virus Of Host Process
Sphingolipid Biosynthetic Process
Endoplasmic Reticulum Unfolded Protein Response
IRE1-mediated Unfolded Protein Response
Positive Regulation Of Viral Genome Replication
Endoplasmic Reticulum-plasma Membrane Tethering
COPII-coated Vesicle Budding
Endoplasmic Reticulum Membrane Organization
Electron Transport Chain
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS
Cerebrospinal fluid levels of Alzheimer's disease-related proteins (
25340798
)
Diastolic blood pressure (
28739976
)
Interacting Genes
41 interacting genes:
AIG1
AQP2
AQP6
CD79A
CYB561
CYBRD1
EBAG9
EBP
ELOVL4
EMD
FAM174A
GLP1R
GPR25
HSD17B13
JAGN1
KCNB1
MTNR1A
OSBPL2
PTGES
REEP4
RETREG3
RMDN2
RNASEK
RNF111
SCN3B
SLC22A1
SLC35C2
STX1A
STX2
STX4
STX5
TMEM101
TMX2
TTC39B
USP20
VAMP1
VAMP2
VHL
VKORC1
ZBTB22
ZDHHC15
59 interacting genes:
ANKRD46
AQP6
BEST2
BET1
BIK
BNIP1
CD79A
CDIPT
CLDN9
CMTM2
CREB3
DARS2
EBP
EDA
EFNA5
EHHADH
ERG28
ERGIC3
FKBP8
GGT7
GIMAP5
GOSR2
GPR152
GPX8
HMOX1
LHFPL5
LMNA
LPAR3
OPRM1
ORMDL2
PLP2
REEP6
RNF5
SCD
SEC22A
SERP2
SLC19A3
SLC35C2
SLC38A7
SLC39A1
SLC39A2
SMIM1
SSMEM1
STX3
SYNJ2BP
TM4SF18
TMEM11
TMEM128
TMEM14B
TMEM179B
TMEM242
TMEM65
TMPPE
TREX1
TSNARE1
UBE2J1
VAPA
VAPB
ZDHHC7
Entrez ID
9217
1534
HPRD ID
09300
02485
Ensembl ID
ENSG00000124164
ENSG00000008283
Uniprot IDs
O95292
Q53XM7
B3KTA1
J3QRH5
P49447
PDB IDs
2MDK
3IKK
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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