DCTN5 and NINL

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		DCTN5	NINL
Description		dynactin subunit 5	ninein like
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleoplasm Centrosome Cytosol Nuclear Membrane	Centrosome Cytosol Microtubule Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Ventricular Septum Development Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Aorta Development Coronary Vasculature Development	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Bipolar disorder ( 17554300)	Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)
Interacting Genes		5 interacting genes: DYNLL1 FATE1 NINL PMEPA1 RBPMS	51 interacting genes: AKAP17A APEX2 AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA ERBB2 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 PRPF18 PRPF3 RBM41 RCOR3 RGS2 RIBC2 RNF40 SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID		84516	22981
HPRD ID		14551	11120
Ensembl ID		ENSG00000166847	ENSG00000101004
Uniprot IDs		Q9BTE1	Q9Y2I6
PDB IDs		5NW4
Enriched GO Terms of Interacting Partners?
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