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ZWINT and NUP54
Data Source:
BioGRID
(two hybrid)
ZWINT
NUP54
Description
ZW10 interacting kinetochore protein
nucleoporin 54
Image
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Body
Dendrite
Nuclear Envelope
Nuclear Membrane
Host Cell
Nuclear Pore Central Transport Channel
Molecular Function
Protein Binding
Protein N-terminus Binding
Protein Binding
Structural Constituent Of Nuclear Pore
Identical Protein Binding
Protein-containing Complex Binding
Biological Process
Mitotic Sister Chromatid Segregation
Mitotic Cell Cycle Checkpoint
Mitotic Spindle Assembly Checkpoint
Cell Division
Establishment Of Localization In Cell
Regulation Of Glycolytic Process
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Targeting
NLS-bearing Protein Import Into Nucleus
Nuclear Pore Organization
Viral Process
Protein Sumoylation
Viral Transcription
Protein Localization To Nuclear Inner Membrane
Regulation Of Protein Import Into Nucleus
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS
Cardiac hypertrophy (
21348951
)
Erosive tooth wear (severe vs non-severe) (
29898447
)
Erosive tooth wear (severe vs none or mild) (
29898447
)
Liver fibrosis (total hepatic collagen content) (
32953199
)
Hippocampal volume (
29274321
)
Interacting Genes
17 interacting genes:
APP
BCAS2
BFSP1
CCHCR1
CLU
DSN1
FAM90A1
KRT75
LIG4
MAFB
MIS12
MSGN1
NDC80
NUP54
PHAX
TSG101
ZW10
46 interacting genes:
AGR2
AP1B1
AP2B1
APC
BPIFA1
C14orf119
C1orf109
C21orf91
CCDC85B
CCHCR1
CDC23
CENPH
DCTN3
DGCR6
EFHC1
EIF3F
EXOC1
EXOC8
HAUS1
HAUS8
HGS
HOMER1
IFT20
KPNA1
KPNB1
KRT15
KRT27
KRT33B
NFKBID
NR3C1
NUP62
NUTF2
OIP5
PKNOX2
SMYD3
SOHLH1
SPG21
SSR1
TACC3
TCHP
TEKT1
TEX12
TPM3
TRIM54
VPS37C
ZWINT
Entrez ID
11130
53371
HPRD ID
18366
06352
Ensembl ID
ENSG00000122952
ENSG00000138750
Uniprot IDs
O95229
Q7Z3B4
PDB IDs
4JNU
4JNV
4JO7
4JO9
5IJN
5IJO
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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