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ZWINT and TSG101
Data Source:
BioGRID
(two hybrid)
ZWINT
TSG101
Description
ZW10 interacting kinetochore protein
tumor susceptibility 101
Image
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Condensed Chromosome Kinetochore
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Body
Dendrite
ESCRT I Complex
Nucleolus
Cytoplasm
Endosome
Early Endosome
Late Endosome
Multivesicular Body
Microtubule Organizing Center
Cytosol
Plasma Membrane
Endosome Membrane
Early Endosome Membrane
Late Endosome Membrane
Host Cell
Extracellular Exosome
Flemming Body
Molecular Function
Protein Binding
Protein N-terminus Binding
DNA Binding
Transcription Corepressor Activity
Protein Binding
Nuclear Receptor Coactivator Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Binding
Protein-containing Complex Binding
Virion Binding
Calcium-dependent Protein Binding
Biological Process
Mitotic Sister Chromatid Segregation
Mitotic Cell Cycle Checkpoint
Mitotic Spindle Assembly Checkpoint
Cell Division
Establishment Of Localization In Cell
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Protein Monoubiquitination
Extracellular Transport
Cell Cycle Arrest
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Endosome To Lysosome Transport
Protein Transport
Endosomal Transport
Macroautophagy
Viral Life Cycle
Keratinocyte Differentiation
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Regulation Of MAP Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Viral Budding
Cell Division
Intracellular Transport Of Virus
Autophagosome Maturation
Regulation Of Viral Release From Host Cell
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Positive Regulation Of Viral Budding Via Host ESCRT Complex
Exosomal Secretion
Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Drugs
Diseases
GWAS
Cardiac hypertrophy (
21348951
)
Erosive tooth wear (severe vs non-severe) (
29898447
)
Erosive tooth wear (severe vs none or mild) (
29898447
)
Liver fibrosis (total hepatic collagen content) (
32953199
)
Interacting Genes
17 interacting genes:
APP
BCAS2
BFSP1
CCHCR1
CLU
DSN1
FAM90A1
KRT75
LIG4
MAFB
MIS12
MSGN1
NDC80
NUP54
PHAX
TSG101
ZW10
120 interacting genes:
AATF
ADRB2
AJUBA
AKAP9
AR
ARRDC1
BAG4
BCAS3
BCR
BIRC2
CAGE1
CBY1
CCDC88B
CCHCR1
CCND3
CDKN1A
CDKN2D
CDS2
CEP55
CEP63
CNOT7
DAXX
DMAP1
DMRTB1
DNMT1
DZIP3
EP300
FAM110A
FAM9B
GGA1
GGA3
GMCL1
GOLM1
HAUS1
HCK
HGS
HSH2D
INCA1
IQGAP1
ITSN1
JUN
KIAA1328
KIF5A
KIFC3
KLK5
KLK6
KRT13
KRT15
KRT16
KRT18
KRT31
KRT34
KRT35
KRT75
LCN2
LENG8
LNX1
LRSAM1
MDM2
MGRN1
MKRN3
MTA3
MZB1
NR3C1
PDCD6IP
PDLIM7
PIAS1
PKNOX2
PPFIBP2
PPP1R13B
PRDM16
PRSS50
QKI
RAD18
RASL10B
RBPMS
RNF111
RNF126
RNF41
ROCK1
SCAMP3
SCARA5
SCGB3A1
SCNN1A
SH3GLB2
SNAPIN
SNF8
SNX32
STK11
SYCE1
TAX1BP1
TEX11
TFF1
TFIP11
THRB
THRSP
TNIP1
TNIP2
TNNT3
TOM1L1
TP53
TRAIP
TRIM23
TRIM35
TRIM46
TRIM54
TRIM74
TRIML2
UBA52
UBC
USHBP1
VPS11
VPS28
VPS36
VPS37A
VPS37B
VPS37C
VPS37D
WASHC1
ZWINT
Entrez ID
11130
7251
HPRD ID
18366
03229
Ensembl ID
ENSG00000122952
ENSG00000074319
Uniprot IDs
O95229
Q99816
PDB IDs
1KPP
1KPQ
1M4P
1M4Q
1S1Q
2F0R
3IV1
3OBQ
3OBS
3OBU
3OBX
3P9G
3P9H
4EJE
4YC1
4ZNY
5VKG
6VME
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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