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UBE2G2 and RNF111
Data Source:
BioGRID
(two hybrid)
UBE2G2
RNF111
Description
ubiquitin conjugating enzyme E2 G2
ring finger protein 111
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum
Lipid Droplet
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
PML Body
Protein-containing Complex
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Identical Protein Binding
Ubiquitin Conjugating Enzyme Activity
Protein Binding
SUMO Polymer Binding
SMAD Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Cellular Response To Interferon-beta
Cellular Protein Catabolic Process
Protein K48-linked Ubiquitination
Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Pattern Specification Process
Protein Ubiquitination
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Ubiquitin-dependent SMAD Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Global Genome Nucleotide-excision Repair
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Downregulation of SMAD2/3:SMAD4 transcriptional activity
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Formation of Incision Complex in GG-NER
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Asperger disorder (
21182207
)
Atopic dermatitis (
25865352
)
Cerebrospinal fluid AB1-42 levels (
28247064
)
Metabolite levels (
22916037
)
Social communication problems (
24047820
)
Interacting Genes
39 interacting genes:
AMFR
ARL14
AUP1
BIRC8
CBL
CNNM3
CPOX
CUL9
ECPAS
FARP2
HBS1L
KDM2A
MDM2
MGRN1
MLLT6
MUL1
NDUFS4
POLR3F
PRKN
RBX1
RC3H1
RC3H2
RFFL
RNF111
RNF146
RNF157
RNF168
RNF26
RNF5
TMEM45B
TRIM3
TRIM43
UBA1
UBA6
UBC
UBE2J2
UBE3A
VAMP8
ZNRF4
54 interacting genes:
ACTN3
ANAPC11
AP2M1
AXIN1
CREB1
CREBBP
CSNK2A1
CTBP1
DTX3L
EDARADD
KRTAP1-1
KRTAP5-9
LCE4A
LRSAM1
MARCHF7
MDFI
MVP
NBPF19
NOTCH2NLA
PAX6
PHF7
PML
PSME3
PTPN3
SDCBP2
SMAD3
SMAD6
SMAD7
SMURF2
SUMO1
SUMO2
SUMO3
TRAF5
TRIM21
TRIM8
TSG101
TSPYL1
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2G2
UBE2I
UBE2K
UBE2M
UBE2N
UBE2Q2
UBE2V1
UBE2W
VAPB
Entrez ID
7327
54778
HPRD ID
04387
09318
Ensembl ID
ENSG00000184787
ENSG00000157450
Uniprot IDs
P60604
A0A024R5T5
Q6ZNA4
PDB IDs
2CYX
2KLY
2LXP
3H8K
4LAD
2KIZ
5LG0
5LG7
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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