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RNF111 and CTBP1
Data Source:
BioGRID
(two hybrid)
RNF111
CTBP1
Description
ring finger protein 111
C-terminal binding protein 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
PML Body
Protein-containing Complex
Nucleus
Nucleoplasm
Cytoplasm
Transcription Repressor Complex
Molecular Function
Protein Binding
SUMO Polymer Binding
SMAD Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
RNA Polymerase II Transcription Corepressor Binding
Transcription Corepressor Activity
Protein Binding
Protein C-terminus Binding
Transcription Factor Binding
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Protein Domain Specific Binding
Identical Protein Binding
NAD Binding
Repressing Transcription Factor Binding
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Pattern Specification Process
Protein Ubiquitination
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Ubiquitin-dependent SMAD Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Global Genome Nucleotide-excision Repair
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Silencing
Protein Phosphorylation
Negative Regulation Of Cell Population Proliferation
Viral Genome Replication
Positive Regulation Of Histone Deacetylation
Negative Regulation Of Histone Acetylation
Negative Regulation Of Transcription, DNA-templated
White Fat Cell Differentiation
Regulation Of Cell Cycle
Negative Regulation Of Histone H4 Acetylation
Pathways
Downregulation of SMAD2/3:SMAD4 transcriptional activity
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Formation of Incision Complex in GG-NER
Antigen processing: Ubiquitination & Proteasome degradation
Deactivation of the beta-catenin transactivating complex
SUMOylation of transcription cofactors
Repression of WNT target genes
Signaling by TCF7L2 mutants
Drugs
Formic acid
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Asperger disorder (
21182207
)
Atopic dermatitis (
25865352
)
Cerebrospinal fluid AB1-42 levels (
28247064
)
Metabolite levels (
22916037
)
Social communication problems (
24047820
)
Type 2 diabetes (
31118516
32499647
)
Interacting Genes
54 interacting genes:
ACTN3
ANAPC11
AP2M1
AXIN1
CREB1
CREBBP
CSNK2A1
CTBP1
DTX3L
EDARADD
KRTAP1-1
KRTAP5-9
LCE4A
LRSAM1
MARCHF7
MDFI
MVP
NBPF19
NOTCH2NLA
PAX6
PHF7
PML
PSME3
PTPN3
SDCBP2
SMAD3
SMAD6
SMAD7
SMURF2
SUMO1
SUMO2
SUMO3
TRAF5
TRIM21
TRIM8
TSG101
TSPYL1
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2G2
UBE2I
UBE2K
UBE2M
UBE2N
UBE2Q2
UBE2V1
UBE2W
VAPB
92 interacting genes:
ACTL6B
AKAP9
APC
ARNT2
ATXN1L
BCAS3
BCL3
BMPR2
BRCA1
CBX4
CDC23
CDKN2D
CEP68
CHD3
CREBBP
CRY2
CTBP2
CTNNA1
DGCR6
DMRTB1
EEF1D
ELAC2
ELK3
EP300
FANCC
FANCF
FANCG
FANCL
FOXP1
FOXP2
FUNDC1
GTF2B
H3-4
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC9
HEMGN
HIC1
HOXB5
HTT
IKZF1
IKZF2
KAT2B
KDM1A
KLF12
KLF3
LCORL
LNX1
MAML2
MAPK9
MARCHF10
MECOM
NME2
NOL4
NOL4L
NOS1
NRIP1
NTAQ1
ORC4
PIAS2
PLCB1
PNN
PRKAA1
PRKCI
RAI2
RB1
RBBP5
RBBP8
RBM14
RCOR1
RNF111
SIN3A
SNRPN
SOBP
SPEN
TBP
TCF4
TEAD4
TERF2
TERF2IP
TGIF1
THAP11
TSHZ3
ZBP1
ZBTB18
ZEB1
ZEB2
ZFPM2
ZNF219
Entrez ID
54778
1487
HPRD ID
09318
04015
Ensembl ID
ENSG00000157450
ENSG00000159692
Uniprot IDs
A0A024R5T5
Q6ZNA4
Q13363
X5D8Y5
PDB IDs
2KIZ
5LG0
5LG7
1MX3
4LCE
4U6Q
4U6S
6CDF
6CDR
Enriched GO Terms of Interacting Partners
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