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UBE2G2 and KDM2A
Data Source:
BioGRID
(two hybrid)
UBE2G2
KDM2A
Description
ubiquitin conjugating enzyme E2 G2
lysine demethylase 2A
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum
Lipid Droplet
Cytosol
Nucleoplasm
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Identical Protein Binding
Ubiquitin Conjugating Enzyme Activity
Transcription Coregulator Activity
Protein Binding
Zinc Ion Binding
Histone Demethylase Activity
Unmethylated CpG Binding
Histone Demethylase Activity (H3-K36 Specific)
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Cellular Response To Interferon-beta
Cellular Protein Catabolic Process
Protein K48-linked Ubiquitination
Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Double-strand Break Repair Via Nonhomologous End Joining
Regulation Of Transcription By RNA Polymerase II
Protein Demethylation
Negative Regulation Of Transcription By Competitive Promoter Binding
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Histone H3-K36 Demethylation
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
HDMs demethylate histones
Drugs
Diseases
GWAS
Height (
28552196
28270201
)
Mean corpuscular volume (
27863252
)
Prostate cancer (
29892016
)
Red blood cell count (
32888494
27863252
)
Interacting Genes
39 interacting genes:
AMFR
ARL14
AUP1
BIRC8
CBL
CNNM3
CPOX
CUL9
ECPAS
FARP2
HBS1L
KDM2A
MDM2
MGRN1
MLLT6
MUL1
NDUFS4
POLR3F
PRKN
RBX1
RC3H1
RC3H2
RFFL
RNF111
RNF146
RNF157
RNF168
RNF26
RNF5
TMEM45B
TRIM3
TRIM43
UBA1
UBA6
UBC
UBE2J2
UBE3A
VAMP8
ZNRF4
11 interacting genes:
ENO1
EP300
FBXO32
FOS
H3-4
H3C14
RELA
SMAD3
SMAD7
UBE2G2
ZNF512B
Entrez ID
7327
22992
HPRD ID
04387
05741
Ensembl ID
ENSG00000184787
ENSG00000173120
Uniprot IDs
P60604
I3VM53
I3VM54
Q9Y2K7
PDB IDs
2CYX
2KLY
2LXP
3H8K
4LAD
2YU1
2YU2
4BBQ
6BYH
6C16
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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