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RNF111 and UBE2D4
Data Source:
BioGRID
(two hybrid, two hybrid)
RNF111
UBE2D4
Description
ring finger protein 111
ubiquitin conjugating enzyme E2 D4 (putative)
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
PML Body
Protein-containing Complex
Ubiquitin Ligase Complex
Nucleus
Molecular Function
Protein Binding
SUMO Polymer Binding
SMAD Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Pattern Specification Process
Protein Ubiquitination
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Ubiquitin-dependent SMAD Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Global Genome Nucleotide-excision Repair
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Downregulation of SMAD2/3:SMAD4 transcriptional activity
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Formation of Incision Complex in GG-NER
Antigen processing: Ubiquitination & Proteasome degradation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Asperger disorder (
21182207
)
Atopic dermatitis (
25865352
)
Cerebrospinal fluid AB1-42 levels (
28247064
)
Metabolite levels (
22916037
)
Social communication problems (
24047820
)
Interacting Genes
54 interacting genes:
ACTN3
ANAPC11
AP2M1
AXIN1
CREB1
CREBBP
CSNK2A1
CTBP1
DTX3L
EDARADD
KRTAP1-1
KRTAP5-9
LCE4A
LRSAM1
MARCHF7
MDFI
MVP
NBPF19
NOTCH2NLA
PAX6
PHF7
PML
PSME3
PTPN3
SDCBP2
SMAD3
SMAD6
SMAD7
SMURF2
SUMO1
SUMO2
SUMO3
TRAF5
TRIM21
TRIM8
TSG101
TSPYL1
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2G2
UBE2I
UBE2K
UBE2M
UBE2N
UBE2Q2
UBE2V1
UBE2W
VAPB
109 interacting genes:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
H3C1
H4C1
IKBKG
INCA1
ITCH
LNX1
LRSAM1
MAGEA11
MAP3K1
MARCHF3
MDM2
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
POLR2E
PRKN
RBCK1
RCHY1
REL
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF216
RNF26
RNF31
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
STUB1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM23
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM62
TRIM8
UBA1
UBC
UBE4A
UBOX5
UBTD1
UBTD2
UFM1
UHRF2
UVSSA
XIAP
ZNRF1
ZNRF2
ZNRF4
Entrez ID
54778
51619
HPRD ID
09318
14242
Ensembl ID
ENSG00000157450
ENSG00000078967
Uniprot IDs
A0A024R5T5
Q6ZNA4
A0A024RA90
Q9UQL0
Q9Y2X8
PDB IDs
2KIZ
5LG0
5LG7
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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