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UBE2G2 and AUP1
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology)
UBE2G2
AUP1
Description
ubiquitin conjugating enzyme E2 G2
AUP1 lipid droplet regulating VLDL assembly factor
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum
Lipid Droplet
Cytosol
Hrd1p Ubiquitin Ligase ERAD-L Complex
Autophagosome
Endoplasmic Reticulum
Lipid Droplet
Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Cytoplasmic Vesicle
Extracellular Exosome
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Identical Protein Binding
Ubiquitin Conjugating Enzyme Activity
Protein Binding
Ubiquitin Conjugating Enzyme Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Binding
Ubiquitin-protein Transferase Activator Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Cellular Response To Interferon-beta
Cellular Protein Catabolic Process
Protein K48-linked Ubiquitination
Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Response To Virus
Viral Process
Ubiquitin-dependent ERAD Pathway
Retrograde Protein Transport, ER To Cytosol
Lipid Droplet Organization
Regulation Of Catalytic Activity
Lipophagy
ER-associated Misfolded Protein Catabolic Process
Lipid Droplet Formation
Protein Localization To Lipid Droplet
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes
39 interacting genes:
AMFR
ARL14
AUP1
BIRC8
CBL
CNNM3
CPOX
CUL9
ECPAS
FARP2
HBS1L
KDM2A
MDM2
MGRN1
MLLT6
MUL1
NDUFS4
POLR3F
PRKN
RBX1
RC3H1
RC3H2
RFFL
RNF111
RNF146
RNF157
RNF168
RNF26
RNF5
TMEM45B
TRIM3
TRIM43
UBA1
UBA6
UBC
UBE2J2
UBE3A
VAMP8
ZNRF4
10 interacting genes:
GPR35
ITGA1
ITGA2
ITGA2B
ITGA5
ITGAM
ITGAV
RNF11
UBC
UBE2G2
Entrez ID
7327
550
HPRD ID
04387
03892
Ensembl ID
ENSG00000184787
ENSG00000115307
Uniprot IDs
P60604
Q9Y679
PDB IDs
2CYX
2KLY
2LXP
3H8K
4LAD
2EKF
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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