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TK1 and ERG28
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
TK1
ERG28
Description
thymidine kinase 1
ergosterol biosynthesis 28 homolog
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Transport Vesicle
Molecular Function
Thymidine Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Identical Protein Binding
Molecular_function
Protein Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Biological Process
Nucleobase-containing Compound Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Phosphorylation
Pyrimidine Nucleoside Salvage
Thymidine Metabolic Process
Protein Homotetramerization
DNA Biosynthetic Process
Biological_process
Sterol Biosynthetic Process
Pathways
G1/S-Specific Transcription
Pyrimidine salvage
Drugs
Dithioerythritol
Thymidine 5'-triphosphate
Diseases
GWAS
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Leukocyte telomere length (
32109421
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
32888494
27863252
28957414
)
Interacting Genes
162 interacting genes:
A1BG
A2M
AAMP
ABHD4
ACTB
ACTL6B
ACTR1B
ADAMTS10
ADD1
AGAP1
ALAS1
ALB
APLP1
APP
ARFGAP1
ATG16L2
ATP5F1B
ATP6V1A
ATXN3
BAG6
BOLA2
BOLA2B
CARHSP1
CCDC115
CCDC90B
CDC20
CDK1
CDK4
CDKN1A
CENPB
CHGB
CLEC3B
COL11A2
COL4A2
COL4A5
COPS6
CPNE6
CRIP2
CRMP1
CSAD
DACT1
DALRD3
DCAF13
DDAH2
DEAF1
DMPK
DOCK7
DRAP1
DUS2
DYNC1I1
DYNC2I1
DYNLT2B
EEF1A1
EIF3G
EIF4A2
EIF6
ERG28
EXT2
EZH2
F13A1
FAF1
FAM20C
FBN3
FGB
FLAD1
FST
GAPDH
GDF9
GDI1
GET3
GLB1
GPCPD1
HADHB
HERC3
HMGXB3
HSPBAP1
IER3IP1
IGHM
IMMT
INPP5K
INTS11
ITSN1
JADE1
JMJD1C
KDM6B
KIF21B
KIF5A
KLHL23
KLHL5
KMT2B
LRIF1
MAGEA4
MAST2
MED31
METTL23
MKI67
MPP1
MPPED1
MRFAP1
MRPL20-AS1
MRPL37
MSH2
NEUROD2
NGFR
NKIRAS2
NMT2
NRBP1
ODC1
PAAF1
PDE4DIP
PJA1
PKM
PLD3
PLXNA3
PPP4C
PROC
PSME1
PTPN4
PTPRK
QARS1
RBBP4
RBM48
REX1BD
RPA1
RPL13
RPS2
RUVBL1
RXRA
SDF4
SEMA5B
SEPTIN6
SETDB1
SEZ6L2
SMC5
SNX1
SP110
SULT1A3
SUMO2
SUMO3
TAF1C
THOC3
TIAM2
TLE1
TMSB4X
TP53
TRIM46
TRMT2A
TSC2
TTC38
TUBA1A
TUBB2A
TUBB3
TYK2
UNC119
UPF2
USP4
WDR18
WDR73
WIZ
ZBTB16
ZNF431
ZXDC
124 interacting genes:
ALDH2
ANXA1
ANXA7
AQP2
AQP3
AQP6
BAIAP2
BCL2L13
BID
BTBD2
CCDC106
CCL18
CD53
CD74
CDC42
CDK5RAP2
CELF3
CLDN5
CLDN7
CLN8
COX17
CRADD
CREB1
CREB3
CREB3L1
CSTF2
CYB561
DYNLL1
EBP
ELOVL4
ERBB2
ERBB3
ERBB4
FAM174A
FAM209A
FAS
FCGR2B
FFAR2
FXR1
FXYD3
GADD45A
GET1
GJB5
GPR152
GPR37L1
GPX8
GSK3B
HMGB1
HNRNPH3
HNRNPUL1
HSD17B11
HSPE1
HTR2C
HYLS1
JAGN1
KCNJ6
KLHL20
LHFPL5
LMNA
LSM2
LYPD5
MAPK8IP2
MFSD14B
MGST3
MPHOSPH6
MRM1
MRPL38
MRPS12
MS4A3
MSMO1
MTERF3
MTNR1B
MUC1
NAT9
NCR3LG1
NDUFA3
NDUFA4L2
NR1H2
NSF
PAFAH1B3
PCDHA4
PDZK1IP1
PEX2
PFN1
PHYHIP
PIGY
POLE2
POLR2C
POLR3F
PPP1R8
PQBP1
PSCA
RAB27A
REEP4
RETREG3
RPS6KA6
S100A8
SAR1A
SAT1
SCN3B
SEPHS1
SERPINB9
SGPL1
SLC10A6
SLC26A6
SLC34A2
SNRPB
SNRPG
SSMEM1
STOM
STX1A
SULT1E1
TFG
TK1
TLCD4
TM4SF19
TMEM106A
TMEM222
TMEM31
TMPRSS2
TSC22D1
TTR
ZFP64
ZNF24
Entrez ID
7083
11161
HPRD ID
01771
05201
Ensembl ID
ENSG00000167900
ENSG00000133935
Uniprot IDs
A0A384MDV9
K7ES52
P04183
Q6FII3
Q86TW5
Q9UKR5
PDB IDs
1W4R
1XBT
2ORV
2WVJ
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Intersection)
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