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ERG28 and CREB3L1
Data Source:
BioGRID
(two hybrid)
ERG28
CREB3L1
Description
ergosterol biosynthesis 28 homolog
cAMP responsive element binding protein 3 like 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Transport Vesicle
Chromatin
Nucleus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Molecular_function
Protein Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
CAMP Response Element Binding
SMAD Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Biological_process
Sterol Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Osteoblast Differentiation
Regulation Of Transcription By RNA Polymerase II
Multicellular Organism Development
Negative Regulation Of Gene Expression
Viral Process
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Extracellular Matrix Constituent Secretion
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Sprouting Angiogenesis
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways
CREB3 factors activate genes
Drugs
Diseases
GWAS
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Apolipoprotein A1 levels (
32203549
)
Autism spectrum disorder or schizophrenia (
28540026
)
Fasting blood glucose (
22581228
)
HDL cholesterol levels (
32203549
)
LDL cholesterol (
30275531
)
Medication use (diuretics) (
31015401
)
Offspring birth weight (
31043758
)
Peripheral artery disease (
31285632
)
Schizophrenia (
29483656
)
Systolic blood pressure (
30578418
)
Interacting Genes
124 interacting genes:
ALDH2
ANXA1
ANXA7
AQP2
AQP3
AQP6
BAIAP2
BCL2L13
BID
BTBD2
CCDC106
CCL18
CD53
CD74
CDC42
CDK5RAP2
CELF3
CLDN5
CLDN7
CLN8
COX17
CRADD
CREB1
CREB3
CREB3L1
CSTF2
CYB561
DYNLL1
EBP
ELOVL4
ERBB2
ERBB3
ERBB4
FAM174A
FAM209A
FAS
FCGR2B
FFAR2
FXR1
FXYD3
GADD45A
GET1
GJB5
GPR152
GPR37L1
GPX8
GSK3B
HMGB1
HNRNPH3
HNRNPUL1
HSD17B11
HSPE1
HTR2C
HYLS1
JAGN1
KCNJ6
KLHL20
LHFPL5
LMNA
LSM2
LYPD5
MAPK8IP2
MFSD14B
MGST3
MPHOSPH6
MRM1
MRPL38
MRPS12
MS4A3
MSMO1
MTERF3
MTNR1B
MUC1
NAT9
NCR3LG1
NDUFA3
NDUFA4L2
NR1H2
NSF
PAFAH1B3
PCDHA4
PDZK1IP1
PEX2
PFN1
PHYHIP
PIGY
POLE2
POLR2C
POLR3F
PPP1R8
PQBP1
PSCA
RAB27A
REEP4
RETREG3
RPS6KA6
S100A8
SAR1A
SAT1
SCN3B
SEPHS1
SERPINB9
SGPL1
SLC10A6
SLC26A6
SLC34A2
SNRPB
SNRPG
SSMEM1
STOM
STX1A
SULT1E1
TFG
TK1
TLCD4
TM4SF19
TMEM106A
TMEM222
TMEM31
TMPRSS2
TSC22D1
TTR
ZFP64
ZNF24
194 interacting genes:
ADAM33
ADGRE2
ADIPOQ
AGPAT3
AGPAT4
AGPAT5
ALG8
ANKRD46
AOC3
APOD
AQP10
AQP2
ARV1
ASGR1
BET1
BMP10
BNIP3
BRICD5
C11orf24
C4orf3
C5
CCL4L2
CD53
CD72
CD99L2
CFHR5
CIAO2A
CLN6
CMTM3
CMTM7
CNIH2
COL8A2
COMT
COX20
CREB3
CREB3L3
CREM
CSGALNACT2
CTSA
CTXN3
CXCL16
CYB561D2
CYBC1
CYP4F2
DDIT3
DOLK
EBP
EMP3
ENTPD3
ERG28
ERMP1
FA2H
FAM3C
FAXDC2
FETUB
FXYD3
FXYD6
GAST
GIMAP1
GIMAP5
GOLT1B
GOSR2
GPR151
GPR25
GPR37L1
HACD2
HIF1A
IL1RL1
INSIG2
ITGAM
JAGN1
KCNK1
LEPROTL1
LHFPL5
LPAR3
LTC4S
MAL
MAL2
MALL
MAN2B2
MARCHF2
MFSD5
MGAM
MGST2
MGST3
MMD2
MS4A1
MS4A13
NAPB
NAT8
NEU1
NINJ1
NINJ2
NRM
NSG1
OLFM4
OR10AG1
ORMDL1
ORMDL2
PAQR6
PEDS1-UBE2V1
PEX16
PGAP2
PGRMC1
PLN
PLP1
PLP2
PLPP4
PLPP6
PLPPR2
PMP22
PRKAB2
PTPN9
RFT1
RHBDD1
RHD
RNASE10
RUNX1T1
RUSF1
SACM1L
SCARF1
SCD
SCGB1D1
SEC22A
SEC22B
SEC61G
SEMA4G
SFXN5
SLC13A2
SLC13A3
SLC16A13
SLC2A3
SLC30A8
SLC35A4
SLC35B1
SLC35B2
SLC35B4
SLC35C2
SLC39A2
SLC39A9
SLC52A1
SLC7A1
SMCO4
SMIM1
SPOCK1
SQLE
STX3
STX7
STX8
SYNGR1
SYNJ2BP
TECR
TEX264
TFRC
TIMM23
TIMMDC1
TLCD1
TMBIM6
TMEM11
TMEM120B
TMEM128
TMEM147
TMEM14A
TMEM14B
TMEM14C
TMEM19
TMEM203
TMEM208
TMEM218
TMEM222
TMEM229B
TMEM234
TMEM239
TMEM50B
TMEM86A
TMIE
TNF
TNFRSF10C
TNMD
TRAM1L1
TSPAN2
TSPO
TSPO2
UBIAD1
UNC93B1
VAMP1
VAMP2
VEZT
VKORC1
WFDC2
YIPF6
ZDHHC15
ZDHHC22
ZFPL1
Entrez ID
11161
90993
HPRD ID
05201
16751
Ensembl ID
ENSG00000133935
ENSG00000157613
Uniprot IDs
Q6FII3
Q86TW5
Q9UKR5
B2RA75
Q96BA8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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