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ERG28 and BID
Data Source:
BioGRID
(two hybrid)
ERG28
BID
Description
ergosterol biosynthesis 28 homolog
BH3 interacting domain death agonist
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Transport Vesicle
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Membrane
Integral Component Of Mitochondrial Membrane
Molecular Function
Molecular_function
Protein Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Death Receptor Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Biological Process
Biological_process
Sterol Biosynthetic Process
Release Of Cytochrome C From Mitochondria
Protein Targeting To Mitochondrion
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Apoptotic Mitochondrial Changes
Positive Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Protein-containing Complex Assembly
Regulation Of Cell Population Proliferation
Signal Transduction In Response To DNA Damage
Mitochondrial ATP Synthesis Coupled Electron Transport
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Neuron Apoptotic Process
Protein-containing Complex Assembly
Establishment Of Protein Localization To Membrane
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Hepatocyte Apoptotic Process
Mitochondrial Outer Membrane Permeabilization
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Fibroblast Apoptotic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Activation of BAD and translocation to mitochondria
Activation and oligomerization of BAK protein
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Activation, translocation and oligomerization of BAX
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Activation, myristolyation of BID and translocation to mitochondria
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Diisocyanate-induced asthma (
25918132
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Interacting Genes
124 interacting genes:
ALDH2
ANXA1
ANXA7
AQP2
AQP3
AQP6
BAIAP2
BCL2L13
BID
BTBD2
CCDC106
CCL18
CD53
CD74
CDC42
CDK5RAP2
CELF3
CLDN5
CLDN7
CLN8
COX17
CRADD
CREB1
CREB3
CREB3L1
CSTF2
CYB561
DYNLL1
EBP
ELOVL4
ERBB2
ERBB3
ERBB4
FAM174A
FAM209A
FAS
FCGR2B
FFAR2
FXR1
FXYD3
GADD45A
GET1
GJB5
GPR152
GPR37L1
GPX8
GSK3B
HMGB1
HNRNPH3
HNRNPUL1
HSD17B11
HSPE1
HTR2C
HYLS1
JAGN1
KCNJ6
KLHL20
LHFPL5
LMNA
LSM2
LYPD5
MAPK8IP2
MFSD14B
MGST3
MPHOSPH6
MRM1
MRPL38
MRPS12
MS4A3
MSMO1
MTERF3
MTNR1B
MUC1
NAT9
NCR3LG1
NDUFA3
NDUFA4L2
NR1H2
NSF
PAFAH1B3
PCDHA4
PDZK1IP1
PEX2
PFN1
PHYHIP
PIGY
POLE2
POLR2C
POLR3F
PPP1R8
PQBP1
PSCA
RAB27A
REEP4
RETREG3
RPS6KA6
S100A8
SAR1A
SAT1
SCN3B
SEPHS1
SERPINB9
SGPL1
SLC10A6
SLC26A6
SLC34A2
SNRPB
SNRPG
SSMEM1
STOM
STX1A
SULT1E1
TFG
TK1
TLCD4
TM4SF19
TMEM106A
TMEM222
TMEM31
TMPRSS2
TSC22D1
TTR
ZFP64
ZNF24
37 interacting genes:
AHCYL1
BAK1
BAX
BCL2
BCL2A1
BCL2L1
BCL2L2
CAPN1
CAPN2
CASP1
CASP10
CASP2
CASP3
CASP8
CRMP1
CRNKL1
CSNK1A1
CSNK1E
CSNK2A1
CSNK2A2
CSNK2B
DDIT4L
ERG28
FBN3
GAPDH
GBP2
GZMB
MCL1
PLEKHM1
RBM48
REL
RPA1
SETDB1
TLE1
TUBB2B
YWHAB
ZHX1
Entrez ID
11161
637
HPRD ID
05201
03590
Ensembl ID
ENSG00000133935
ENSG00000015475
Uniprot IDs
Q6FII3
Q86TW5
Q9UKR5
A8ASI8
B2ZP79
B3KT21
P55957
PDB IDs
1ZY3
2BID
2KBW
2M5B
2M5I
4BD2
4QVE
4ZEQ
4ZIG
4ZII
5AJJ
5C3F
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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