ERG28 and AQP3

Data Source:
BioGRID (two hybrid)

		ERG28	AQP3
Description		ergosterol biosynthesis 28 homolog	aquaporin 3 (Gill blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Transport Vesicle	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane
	Molecular Function	Molecular_function Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Identical Protein Binding
	Biological Process	Biological_process Sterol Biosynthetic Process	Positive Regulation Of Immune System Process Renal Water Homeostasis Water Transport Glycerol Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport Cellular Response To Oxygen-glucose Deprivation
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
Drugs			Sennosides
Diseases
GWAS			Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)
Interacting Genes		124 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 AQP3 AQP6 BAIAP2 BCL2L13 BID BTBD2 CCDC106 CCL18 CD53 CD74 CDC42 CDK5RAP2 CELF3 CLDN5 CLDN7 CLN8 COX17 CRADD CREB1 CREB3 CREB3L1 CSTF2 CYB561 DYNLL1 EBP ELOVL4 ERBB2 ERBB3 ERBB4 FAM174A FAM209A FAS FCGR2B FFAR2 FXR1 FXYD3 GADD45A GET1 GJB5 GPR152 GPR37L1 GPX8 GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSD17B11 HSPE1 HTR2C HYLS1 JAGN1 KCNJ6 KLHL20 LHFPL5 LMNA LSM2 LYPD5 MAPK8IP2 MFSD14B MGST3 MPHOSPH6 MRM1 MRPL38 MRPS12 MS4A3 MSMO1 MTERF3 MTNR1B MUC1 NAT9 NCR3LG1 NDUFA3 NDUFA4L2 NR1H2 NSF PAFAH1B3 PCDHA4 PDZK1IP1 PEX2 PFN1 PHYHIP PIGY POLE2 POLR2C POLR3F PPP1R8 PQBP1 PSCA RAB27A REEP4 RETREG3 RPS6KA6 S100A8 SAR1A SAT1 SCN3B SEPHS1 SERPINB9 SGPL1 SLC10A6 SLC26A6 SLC34A2 SNRPB SNRPG SSMEM1 STOM STX1A SULT1E1 TFG TK1 TLCD4 TM4SF19 TMEM106A TMEM222 TMEM31 TMPRSS2 TSC22D1 TTR ZFP64 ZNF24	28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN
Entrez ID		11161	360
HPRD ID		05201	08970
Ensembl ID		ENSG00000133935	ENSG00000165272
Uniprot IDs		Q6FII3 Q86TW5 Q9UKR5	A0A2R8Y2R4 Q92482
PDB IDs
Enriched GO Terms of Interacting Partners?
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