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SUV39H1 and RSPO2
Data Source:
BioGRID
(two hybrid)
SUV39H1
RSPO2
Description
suppressor of variegation 3-9 homolog 1
R-spondin 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Heterochromatin
Condensed Nuclear Chromosome
Nucleus
Nuclear Lamina
Nucleoplasm
Chromatin Silencing Complex
RDNA Heterochromatin
Extracellular Region
Cell Surface
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
S-adenosylmethionine-dependent Methyltransferase Activity
Histone-lysine N-methyltransferase Activity
Histone Methyltransferase Activity
Histone Methyltransferase Activity (H3-K9 Specific)
Protein N-terminus Binding
Signaling Receptor Binding
Protein Binding
Heparin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
RDNA Heterochromatin Assembly
Chromatin Organization
RRNA Processing
Cellular Response To DNA Damage Stimulus
Cell Cycle
Viral Process
Cell Differentiation
Histone Lysine Methylation
Histone H3-K9 Dimethylation
Histone H3-K9 Trimethylation
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Rhythmic Process
Cellular Response To Hypoxia
Osteoblast Differentiation
Wnt Signaling Pathway
Positive Regulation Of Wnt Signaling Pathway
Bone Mineralization
Embryonic Forelimb Morphogenesis
Embryonic Hindlimb Morphogenesis
Negative Regulation Of Odontogenesis Of Dentin-containing Tooth
Limb Development
Lung Growth
Epithelial Tube Branching Involved In Lung Morphogenesis
Trachea Cartilage Morphogenesis
Dopaminergic Neuron Differentiation
Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
PKMTs methylate histone lysines
SIRT1 negatively regulates rRNA expression
Regulation of FZD by ubiquitination
Drugs
Diseases
GWAS
Acute lymphoblastic leukemia (childhood) (
22076464
)
Blond vs. brown/black hair color (
30531825
)
Blood protein levels (
30072576
)
Brain morphology (MOSTest) (
32665545
)
Dupuytren's disease (
28886342
21732829
)
Heel bone mineral density (
30598549
)
Hip circumference adjusted for BMI (
28552196
)
Intake of total sugars (
31005972
)
Macular thickness (
30535121
)
Male-pattern baldness (
29146897
28196072
)
Ossification of the posterior longitudinal ligament of the spine (
25064007
)
Interacting Genes
138 interacting genes:
ATE1
ATF3
ATP6V1B1
BAHD1
BCL11B
C4orf17
C8orf74
CBX1
CBX3
CBX4
CBX5
CDC23
CDCA4
CDCA7L
CEP70
CFAP100
CLK3
CRBN
CREBBP
CRELD2
DBF4B
DCAF8
DDB1
DNMT1
DNMT3A
DNMT3B
DVL3
ELOF1
EP300
ESR1
EZH2
FGD5
FOXR2
FRMD6
FUS
FYN
GOLGA6L9
GPATCH2L
GTF2H2C_2
GTPBP2
H3-3A
H3-4
H3-5
H3C1
H3C15
HDAC1
HDAC2
HDAC3
HDAC5
HOOK2
HOXA1
HOXC4
ID1
ID2
IGFBP4
IL16
ING4
INTS2
KDM1A
KLF15
KLHDC4
KLHL20
KRTAP10-7
KRTAP10-8
LDHAL6B
LENG8
LHX8
LINC02875
LNX1
LOXL4
LZTS2
MALT1
MBD1
MBD4
MCRS1
MSANTD3
MTF2
MTO1
MYOD1
NR1H2
NR1H3
ODAD3
OPA3
PADI6
PHF19
PML
PNKP
PPP1R16A
PRIM2
PRMT6
PSMC1
RASSF1
RASSF2
RB1
RBBP4
RBBP7
RBL1
RBL2
RIN3
RRP8
RSPO2
RUNX1
SBF1
SLFN12
SMAD1
SMAD5
SPATA24
SPRED1
SPSB1
SRGAP3
STX11
STX19
TEKT4
TEX35
THRA
TMEM11
TNFAIP1
TNS2
TRIM41
U2AF1
WDFY3
WIZ
ZBTB2
ZBTB24
ZCCHC17
ZKSCAN5
ZNF165
ZNF417
ZNF436
ZNF438
ZNF451
ZNF557
ZNF581
ZNF649
ZNF670
ZNF829
ZRANB1
ZSCAN9
19 interacting genes:
CATSPER1
CYSRT1
HOXA1
JMJD6
KRTAP10-1
KRTAP10-4
KRTAP10-6
KRTAP10-7
KRTAP10-9
KRTAP12-3
LGR4
LGR5
PLEKHF2
RNF43
SLC39A7
SUV39H1
ZNF330
ZNF837
ZNRF3
Entrez ID
6839
340419
HPRD ID
02221
17536
Ensembl ID
ENSG00000101945
ENSG00000147655
Uniprot IDs
O43463
B3KVP3
Q6UXX9
PDB IDs
3MTS
Enriched GO Terms of Interacting Partners
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