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SUV39H1 and ZNF417
Data Source:
BioGRID
(two hybrid)
SUV39H1
ZNF417
Description
suppressor of variegation 3-9 homolog 1
zinc finger protein 417
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Heterochromatin
Condensed Nuclear Chromosome
Nucleus
Nuclear Lamina
Nucleoplasm
Chromatin Silencing Complex
RDNA Heterochromatin
Nucleus
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
S-adenosylmethionine-dependent Methyltransferase Activity
Histone-lysine N-methyltransferase Activity
Histone Methyltransferase Activity
Histone Methyltransferase Activity (H3-K9 Specific)
Protein N-terminus Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
RDNA Heterochromatin Assembly
Chromatin Organization
RRNA Processing
Cellular Response To DNA Damage Stimulus
Cell Cycle
Viral Process
Cell Differentiation
Histone Lysine Methylation
Histone H3-K9 Dimethylation
Histone H3-K9 Trimethylation
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Rhythmic Process
Cellular Response To Hypoxia
Regulation Of Transcription By RNA Polymerase II
Pathways
PKMTs methylate histone lysines
SIRT1 negatively regulates rRNA expression
Generic Transcription Pathway
Drugs
Diseases
GWAS
Depression in smokers (
30219690
)
Interacting Genes
138 interacting genes:
ATE1
ATF3
ATP6V1B1
BAHD1
BCL11B
C4orf17
C8orf74
CBX1
CBX3
CBX4
CBX5
CDC23
CDCA4
CDCA7L
CEP70
CFAP100
CLK3
CRBN
CREBBP
CRELD2
DBF4B
DCAF8
DDB1
DNMT1
DNMT3A
DNMT3B
DVL3
ELOF1
EP300
ESR1
EZH2
FGD5
FOXR2
FRMD6
FUS
FYN
GOLGA6L9
GPATCH2L
GTF2H2C_2
GTPBP2
H3-3A
H3-4
H3-5
H3C1
H3C15
HDAC1
HDAC2
HDAC3
HDAC5
HOOK2
HOXA1
HOXC4
ID1
ID2
IGFBP4
IL16
ING4
INTS2
KDM1A
KLF15
KLHDC4
KLHL20
KRTAP10-7
KRTAP10-8
LDHAL6B
LENG8
LHX8
LINC02875
LNX1
LOXL4
LZTS2
MALT1
MBD1
MBD4
MCRS1
MSANTD3
MTF2
MTO1
MYOD1
NR1H2
NR1H3
ODAD3
OPA3
PADI6
PHF19
PML
PNKP
PPP1R16A
PRIM2
PRMT6
PSMC1
RASSF1
RASSF2
RB1
RBBP4
RBBP7
RBL1
RBL2
RIN3
RRP8
RSPO2
RUNX1
SBF1
SLFN12
SMAD1
SMAD5
SPATA24
SPRED1
SPSB1
SRGAP3
STX11
STX19
TEKT4
TEX35
THRA
TMEM11
TNFAIP1
TNS2
TRIM41
U2AF1
WDFY3
WIZ
ZBTB2
ZBTB24
ZCCHC17
ZKSCAN5
ZNF165
ZNF417
ZNF436
ZNF438
ZNF451
ZNF557
ZNF581
ZNF649
ZNF670
ZNF829
ZRANB1
ZSCAN9
169 interacting genes:
ADAMTSL4
AXIN2
BEGAIN
BEND5
BEX3
BHLHB9
BICD2
C4orf17
CARD9
CBY2
CCDC125
CCDC136
CCDC57
CCDC85B
CCNDBP1
CDR2
CDR2L
CEP44
CEP70
CEP72
CEP85L
CHRDL2
COG6
CSRNP1
CYSRT1
DEF8
DVL3
EFS
EZHIP
FAM221A
FHL2
FHL3
FHL5
FRS3
FSD2
FXR1
GOLGA2
GOLGA6L9
HMBOX1
HOMEZ
HOOK2
HOXA1
HSF2BP
IGFBP6
IHO1
IKZF1
INKA1
JADE2
JRK
KAT5
KATNBL1
KCTD7
KIF9
KIFC3
KLC3
KRT15
KRT31
KRT35
KRT38
KRT39
KRT40
KRTAP1-3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-9
KXD1
LHX3
LIMS1
LMO1
LURAP1
LZTS1
LZTS2
MAGEA8
MAST2
MCC
MCCD1
MDFI
MEIS3
MEOX2
MID2
MIIP
MRFAP1L1
MTUS2
MYF5
MYLIP
NAB2
NBPF19
NDEL1
NDUFB7
NINL
NKAPL
NKX3-1
NOTCH2NLA
OIP5
PHC2
PICK1
PIH1D2
PLSCR1
PNMA2
PRICKLE4
PRPF31
RCN3
REL
RHOQ
RNF187
RORB
RPGRIP1
RUNDC3A
SH2B2
SMARCD1
SMYD5
SPRED1
SPRED2
SPRY1
SPRY2
SSX2IP
STX11
SUV39H1
TADA2A
TCF4
TEKT4
TFIP11
TLE5
TMCC2
TNS2
TRAF1
TRAF2
TRIB3
TRIM23
TRIM27
TRIM36
TRIM37
TRIM41
TRIM54
TSC1
TSGA10
TXNDC11
U2AF1
U2AF1L5
USHBP1
VPS16
VPS52
VWC2
ZBTB1
ZBTB10
ZBTB43
ZBTB8A
ZBTB9
ZNF165
ZNF19
ZNF20
ZNF547
ZNF572
ZNF587
ZNF69
ZNF71
ZNF768
ZNF774
ZNF837
ZNF85
ZRANB1
Entrez ID
6839
147687
HPRD ID
02221
18341
Ensembl ID
ENSG00000101945
ENSG00000173480
Uniprot IDs
O43463
M0R230
Q8TAU3
PDB IDs
3MTS
Enriched GO Terms of Interacting Partners
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