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SUV39H1 and ZNF438
Data Source:
BioGRID
(two hybrid)
SUV39H1
ZNF438
Description
suppressor of variegation 3-9 homolog 1
zinc finger protein 438
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Heterochromatin
Condensed Nuclear Chromosome
Nucleus
Nuclear Lamina
Nucleoplasm
Chromatin Silencing Complex
RDNA Heterochromatin
Nucleus
Nucleoplasm
Cytosol
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
S-adenosylmethionine-dependent Methyltransferase Activity
Histone-lysine N-methyltransferase Activity
Histone Methyltransferase Activity
Histone Methyltransferase Activity (H3-K9 Specific)
Protein N-terminus Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
RDNA Heterochromatin Assembly
Chromatin Organization
RRNA Processing
Cellular Response To DNA Damage Stimulus
Cell Cycle
Viral Process
Cell Differentiation
Histone Lysine Methylation
Histone H3-K9 Dimethylation
Histone H3-K9 Trimethylation
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Rhythmic Process
Cellular Response To Hypoxia
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
PKMTs methylate histone lysines
SIRT1 negatively regulates rRNA expression
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Congenital left-sided heart lesions (maternal effect) (
25138779
)
Heel bone mineral density (
30598549
)
Height (
25429064
31562340
)
Multiple sclerosis (
31604244
21833088
)
Physiological traits (
31902109
)
Pulse pressure (
27841878
)
Response to fenofibrate (triglyceride levels) (
27002377
)
Rheumatoid arthritis (
30423114
24390342
)
Interacting Genes
138 interacting genes:
ATE1
ATF3
ATP6V1B1
BAHD1
BCL11B
C4orf17
C8orf74
CBX1
CBX3
CBX4
CBX5
CDC23
CDCA4
CDCA7L
CEP70
CFAP100
CLK3
CRBN
CREBBP
CRELD2
DBF4B
DCAF8
DDB1
DNMT1
DNMT3A
DNMT3B
DVL3
ELOF1
EP300
ESR1
EZH2
FGD5
FOXR2
FRMD6
FUS
FYN
GOLGA6L9
GPATCH2L
GTF2H2C_2
GTPBP2
H3-3A
H3-4
H3-5
H3C1
H3C15
HDAC1
HDAC2
HDAC3
HDAC5
HOOK2
HOXA1
HOXC4
ID1
ID2
IGFBP4
IL16
ING4
INTS2
KDM1A
KLF15
KLHDC4
KLHL20
KRTAP10-7
KRTAP10-8
LDHAL6B
LENG8
LHX8
LINC02875
LNX1
LOXL4
LZTS2
MALT1
MBD1
MBD4
MCRS1
MSANTD3
MTF2
MTO1
MYOD1
NR1H2
NR1H3
ODAD3
OPA3
PADI6
PHF19
PML
PNKP
PPP1R16A
PRIM2
PRMT6
PSMC1
RASSF1
RASSF2
RB1
RBBP4
RBBP7
RBL1
RBL2
RIN3
RRP8
RSPO2
RUNX1
SBF1
SLFN12
SMAD1
SMAD5
SPATA24
SPRED1
SPSB1
SRGAP3
STX11
STX19
TEKT4
TEX35
THRA
TMEM11
TNFAIP1
TNS2
TRIM41
U2AF1
WDFY3
WIZ
ZBTB2
ZBTB24
ZCCHC17
ZKSCAN5
ZNF165
ZNF417
ZNF436
ZNF438
ZNF451
ZNF557
ZNF581
ZNF649
ZNF670
ZNF829
ZRANB1
ZSCAN9
68 interacting genes:
ACOT7
BACH2
BANP
BBC3
BYSL
CDCA7L
CDK18
CEP19
CYSRT1
DMRT3
DPH3
ESRRG
FARS2
FRS3
FXR1
GOLGA2
GOLGA6L9
HAPLN2
KCTD7
KRT40
KRTAP10-1
LGALS14
MAGOHB
MCC
MDFI
MID2
MORF4L1
MORN3
MRPL11
MTUS2
MYLIP
MYO15B
NEK6
NXF1
PIBF1
PICK1
PIH1D2
PLEKHN1
PNMA1
PRMT7
PSMB1
RABEP1
RECK
RPP25
SCNM1
SET
SMARCD1
SPANXN2
SSX2IP
SUV39H1
SYT17
TBC1D22B
TP53BP2
TRAF2
TRAPPC2
TRAPPC2B
TRIM50
TSGA10
TSTD2
YES1
ZBTB8A
ZNF143
ZNF17
ZNF202
ZNF526
ZNF629
ZNF648
ZRANB1
Entrez ID
6839
220929
HPRD ID
02221
11247
Ensembl ID
ENSG00000101945
ENSG00000183621
Uniprot IDs
O43463
Q5T427
Q7Z4V0
PDB IDs
3MTS
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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