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SUV39H1 and H3-5
Data Source:
BioGRID
(two hybrid)
SUV39H1
H3-5
Description
suppressor of variegation 3-9 homolog 1
H3.5 histone
Image
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Heterochromatin
Condensed Nuclear Chromosome
Nucleus
Nuclear Lamina
Nucleoplasm
Chromatin Silencing Complex
RDNA Heterochromatin
Nucleosome
Euchromatin
Nucleus
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
S-adenosylmethionine-dependent Methyltransferase Activity
Histone-lysine N-methyltransferase Activity
Histone Methyltransferase Activity
Histone Methyltransferase Activity (H3-K9 Specific)
Protein N-terminus Binding
Protein Binding
Nucleosomal DNA Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
RDNA Heterochromatin Assembly
Chromatin Organization
RRNA Processing
Cellular Response To DNA Damage Stimulus
Cell Cycle
Viral Process
Cell Differentiation
Histone Lysine Methylation
Histone H3-K9 Dimethylation
Histone H3-K9 Trimethylation
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Rhythmic Process
Cellular Response To Hypoxia
Positive Regulation Of Cell Growth
Pathways
PKMTs methylate histone lysines
SIRT1 negatively regulates rRNA expression
Drugs
Diseases
GWAS
Interacting Genes
138 interacting genes:
ATE1
ATF3
ATP6V1B1
BAHD1
BCL11B
C4orf17
C8orf74
CBX1
CBX3
CBX4
CBX5
CDC23
CDCA4
CDCA7L
CEP70
CFAP100
CLK3
CRBN
CREBBP
CRELD2
DBF4B
DCAF8
DDB1
DNMT1
DNMT3A
DNMT3B
DVL3
ELOF1
EP300
ESR1
EZH2
FGD5
FOXR2
FRMD6
FUS
FYN
GOLGA6L9
GPATCH2L
GTF2H2C_2
GTPBP2
H3-3A
H3-4
H3-5
H3C1
H3C15
HDAC1
HDAC2
HDAC3
HDAC5
HOOK2
HOXA1
HOXC4
ID1
ID2
IGFBP4
IL16
ING4
INTS2
KDM1A
KLF15
KLHDC4
KLHL20
KRTAP10-7
KRTAP10-8
LDHAL6B
LENG8
LHX8
LINC02875
LNX1
LOXL4
LZTS2
MALT1
MBD1
MBD4
MCRS1
MSANTD3
MTF2
MTO1
MYOD1
NR1H2
NR1H3
ODAD3
OPA3
PADI6
PHF19
PML
PNKP
PPP1R16A
PRIM2
PRMT6
PSMC1
RASSF1
RASSF2
RB1
RBBP4
RBBP7
RBL1
RBL2
RIN3
RRP8
RSPO2
RUNX1
SBF1
SLFN12
SMAD1
SMAD5
SPATA24
SPRED1
SPSB1
SRGAP3
STX11
STX19
TEKT4
TEX35
THRA
TMEM11
TNFAIP1
TNS2
TRIM41
U2AF1
WDFY3
WIZ
ZBTB2
ZBTB24
ZCCHC17
ZKSCAN5
ZNF165
ZNF417
ZNF436
ZNF438
ZNF451
ZNF557
ZNF581
ZNF649
ZNF670
ZNF829
ZRANB1
ZSCAN9
15 interacting genes:
DAXX
DNAJC9
FBLIM1
KAT6A
KDM1A
KDM4B
NASP
NSD3
PRMT5
PRMT6
PRMT7
SETMAR
SMYD1
SMYD3
SUV39H1
Entrez ID
6839
440093
HPRD ID
02221
18443
Ensembl ID
ENSG00000101945
ENSG00000188375
Uniprot IDs
O43463
Q6NXT2
PDB IDs
3MTS
2PUY
3KV4
4Z5T
5BWN
5BWO
5F6K
5I3L
6OI3
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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