RSPO2 and ZNF330

Data Source:
BioGRID (two hybrid)

		RSPO2	ZNF330
Description		R-spondin 2	zinc finger protein 330
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Surface	Chromosome, Centromeric Region Nucleus Nucleolus Midbody
	Molecular Function	Signaling Receptor Binding Protein Binding Heparin Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Bone Mineralization Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Negative Regulation Of Odontogenesis Of Dentin-containing Tooth Limb Development Lung Growth Epithelial Tube Branching Involved In Lung Morphogenesis Trachea Cartilage Morphogenesis Dopaminergic Neuron Differentiation Positive Regulation Of Canonical Wnt Signaling Pathway	Biological_process
Pathways		Regulation of FZD by ubiquitination
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Intake of total sugars ( 31005972) Macular thickness ( 30535121) Male-pattern baldness ( 29146897 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)	Conduct disorder ( 20585324) Malaria ( 31844061)
Interacting Genes		19 interacting genes: CATSPER1 CYSRT1 HOXA1 JMJD6 KRTAP10-1 KRTAP10-4 KRTAP10-6 KRTAP10-7 KRTAP10-9 KRTAP12-3 LGR4 LGR5 PLEKHF2 RNF43 SLC39A7 SUV39H1 ZNF330 ZNF837 ZNRF3	52 interacting genes: ADAMTSL4 CCDC33 CCN3 CFP CHIC2 CNNM3 CREB5 CYSRT1 KLF15 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP13-3 KRTAP5-7 MDFI MEOX2 NBPF19 NDUFB7 NOTCH2NLA NR4A3 OTX1 PBX4 PICK1 RBAK RSPO2 RSPO4 RWDD4 SPATA3 SPRY1 STK16 STX19 SUFU TCL1B TLE5 TRIM42 ZBTB42 ZNF23 ZNF250 ZNF408 ZNF426 ZNF440 ZNF460 ZNF547 ZNF587 ZNF655 ZNF664 ZNF669 ZNF683 ZNF688 ZNF764 ZNF768 ZNF837
Entrez ID		340419	27309
HPRD ID		17536	15775
Ensembl ID		ENSG00000147655	ENSG00000109445
Uniprot IDs		B3KVP3 Q6UXX9	B4DFG9 Q53EN0 Q9Y3S2
PDB IDs
Enriched GO Terms of Interacting Partners?
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