RSPO2 and KRTAP10-4

Data Source:
BioGRID (two hybrid)

		RSPO2	KRTAP10-4
Description		R-spondin 2	keratin associated protein 10-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Surface	Cytosol Keratin Filament
	Molecular Function	Signaling Receptor Binding Protein Binding Heparin Binding	Protein Binding
	Biological Process	Osteoblast Differentiation Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Bone Mineralization Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Negative Regulation Of Odontogenesis Of Dentin-containing Tooth Limb Development Lung Growth Epithelial Tube Branching Involved In Lung Morphogenesis Trachea Cartilage Morphogenesis Dopaminergic Neuron Differentiation Positive Regulation Of Canonical Wnt Signaling Pathway	Keratinization
Pathways		Regulation of FZD by ubiquitination
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Intake of total sugars ( 31005972) Macular thickness ( 30535121) Male-pattern baldness ( 29146897 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)	Leukocyte telomere length ( 32109421)
Interacting Genes		19 interacting genes: CATSPER1 CYSRT1 HOXA1 JMJD6 KRTAP10-1 KRTAP10-4 KRTAP10-6 KRTAP10-7 KRTAP10-9 KRTAP12-3 LGR4 LGR5 PLEKHF2 RNF43 SLC39A7 SUV39H1 ZNF330 ZNF837 ZNRF3	10 interacting genes: CATSPER1 E4F1 HOXA1 IGSF8 JOSD1 RSPO2 WT1 ZNF32 ZNF625 ZSCAN26
Entrez ID		340419	386672
HPRD ID		17536	11190
Ensembl ID		ENSG00000147655	ENSG00000215454
Uniprot IDs		B3KVP3 Q6UXX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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